Synthesis and Purification of Acetylsalicylic Acid (ASA or Aspirin) Background Salicylic acid is a phenol as well as a carboxylic acid. It can therefore undergo two different types of esterification reactions‚ creating an ester either with the hydroxyl or with the acid. In the presence of acetic anhydride‚ acetylsalicylic acid (aspirin or ASA) is formed. Correspondingly‚ an excess of methanol will form methyl salicylate‚ which is also an analgesic. In this experiment‚ we shall use
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Organic Synthesis of Aspirin Abstract The purpose of this experiment is to synthesize a common organic product called acetylsalicylic acid (aspirin)‚ and to become familiar with the optimum conditions needed for successful yields. Aspirin is produced from an acid catalyzed reaction between salicylic acid with acetic anhydride. The crystalline aspirin is synthesized and purified by recrystallization‚ although there is not a hundred percent yield due to sources of error. Introduction Aspirin is a
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INTRODUCTION: Penicillin is the basis for most of the antibiotics in the world just as aspirin is the basis for many drugs. Therefore‚ if there had been only two drugs to invent‚ it would be down to penicillin and aspirin. Hippocrates‚ the father of modern medicine lived sometime between 460 B.C and 377 B.C. Hippocrates has left historical records of pain relief treatments‚ including the use of a powder made from the bark and leaves of the willow tree to help heal headaches‚ pains and fevers.
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Synthesis of Aspirin and Oil of Wintergreen Janelle Alyssa P. Prudente De La Salle University-Dasmariñas Dasmariñas City‚ Cavite‚ Philippines ABSTRACT In this experiment‚ acetylsalicylic acid commonly known as aspirin and methyl salicylate‚ commonly known as oil of wintergreen‚ was synthesized from salicylic acid. This study will show that it is possible to show two very different organic compounds from the same common starting material. For the synthesis of aspirin‚ salicylic acid
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Microscale Synthesis of Acetylsalicylic Acid [pic] Introduction: Acetylsalicylic acid is a wonder drug par excellence. It is widely used as an analgesic (pain reliever) and fever depressant. It also reduces inflammation and may even prevent heart attacks. It has a few side effects for some people‚ yet it is safe enough to be sold without a prescription. Because it is easy to prepare‚ aspirin is one of the most inexpensive drugs available. It is produced in vast amounts. In fact‚ industry
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Experimental Synthesis of Aspirin and Melting Point Purity Analysis Donald Yeargin CH 222‚ Section 24221 Department of Chemistry Portland Community College Portland‚ OR Abstract The various methods available to synthesize aspirin lead to the need to examine and evaluate production efficiency and purity. The purpose of our experiment was to synthesize acetyl salicylic acid (aspirin) and then determine the relative purity of the synthesized sample by observing the melting point temperature
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Date Experiment conducted: 05/02/2009 Date Report Written: 08/02/2009 Synthesis of Acetyl salicylic acid (Aspirin) Abstract Introduction: The following report contains information on how to produce aspirin. The experiment has been carried out on a small laboratory scale. The experiment starts by combining such chemicals such as salicylic acid and acetic anhydride. The synthesis of aspirin is classified as an esterification reaction. This is a substitution reaction where the alcohol group
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b. Characterization of Aspirin B. Set – up Fig. 11.1. Suction Filtration Set – up C. Table 11.1 List of Necessary Chemicals Sample Structure Purpose Physical Properties Hazards Salicylic Acid Starting Material Appearance: white powder Molar Mass: 138.12 g/mol Melting Point: 1590C Boiling Point: 2110C Density: 1.44 g/cm3 Mildly irritating (pulmonary irritants). Harmful by inhalation‚ ingestion and through skin absorption. Acetic Anhydride
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Lab Report Introduction This lab has the following two concepts: synthesis of acetylsalicylic acid and analysis of acetylsalicylic acid. Synthesis is a purposeful execution of chemical reactions to obtain a product. This concept is used in the first part of the lab; when we have to produce crystals of aspirin. Analysis is the separation‚ identification‚ and quantification of the chemical components of natural and artificial materials. This concept is used throughout the lab when we are analyzing
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Measuring Devices Other Equipment Procedure Synthesis of Aspirin Crystalizing the Aspirin Recrystallizing the Crude Aspirin Finding the Melting Point Range Safety Precautions Acetic Anhydride Sulphuric and Salicylic Acid Heating Observations Mass of Aspirin Synthesized Melting Point Calculations Percentage Yield Maximum Yield Crude Product Final Product Melting Range Percentage Error Crude Product Final Product Conclusion and Analysis Discussion Suggested Modifications to Procedure
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