Synthesis of Aspirin Name: Xuanyi Li Teaching assistant: Deirdre Zwilling November 15‚ 2009 Purpose: To synthesize aspirin‚ a common analgesic drug‚ via nucleophilic acid-catalyzed substitution reaction of salicyclic acid with acetic anhydride. The whole reaction is catalyzed by phosphoric acid. (The experiment involved three parts: The synthesis of aspirin‚ the isolation and purification of aspirin‚ and the estimation of the purity of the final product.) [pic] Procedure[1]: A mixture
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Synthesis of Aspirin Learning Goals 1. To synthesize aspirin from salicylic acid and acetic anhydride. 2. To purify the crude product by Recrystallization. Introduction Most drugs are chemical compounds which are described as "organic compounds" because they are comprised primarily of the elements carbon‚ hydrogen and oxygen. The present experiment will be the synthesis of a familiar organic compound called aspirin. The common chemical name is acetylsalicylic acid. Aspirin‚ the
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Jeana Greaves Chem3301-112 June 19‚ 2013 Synthesis of Aspirin from Methyl Salicylate Introduction The synthesis of Aspirin (Acetyl Salicyclic Acid) began with methyl salicylate and sodium hydroxide as the reagent. The polar oxygen accepts the electrons from now positively charged hydrogen. The positively charged sodium disassociates leaving the hydroxide ion with a negative Scheme 1 shows the mechanisms that were demonstrated during the synthesis of Aspirin. charge that attracts to the positively
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U‚ and C for the nucleotides guanine‚ adenine‚ uracil and cytosine) that directs synthesis of specific proteins‚ while many viruses encode their genetic information using an RNA genome. Some RNA molecules play an active role within cells by catalyzing biological reactions‚ controlling gene expression‚ or sensing and communicating responses to cellular signals. One of these active processes is protein synthesis‚ a universal function whereby mRNA molecules direct the assembly of proteins on ribosomes
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The first synthetic sweetener‚ saccharin‚ was discovered five years prior to Dulcin. The discovery of Dulcin occurred in 1883. Approximately seven years after it’s discovery‚ J.D. Reidel‚ of Berlin‚ was able to synthesis Dulcin at a reasonable cost. Once it became possible to synthesis at a reasonable cost‚ mass production of the sweetener began. Dulcin was favored over its competitor‚ Saccharin‚ because it did not possess a bitter aftertaste. For a very brief period of time Dulcin was marketed
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Synthesis Conclusion: Conclusion: As we can see‚ the sources show us that during the Enlightenment period money was very important. It shows that during the time people would do merely anything for money‚ even force their children into arranged marriages or‚ as Voltaire suggest satirically‚ sell them as a food source. Parents or even the brides and grooms themselves would arranged marriages for economic gain. This was not always the case. We have learned from She Stoops to Conquer that‚ although
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EXERCISE 11 SYNTHESIS OF ASPIRIN MARAVILLA‚ Ana Mikaela B Group 4 CHEM 40.1 1L Date performed: September 30‚ 2013 Date submitted: October 7‚ 2013 VI. RESULTS AND DISCUSSION Aspirin is prepared by the esterification of salicylic acid with acetic anhydride under acidic conditions. The phenol group in salicylic acid is replaced by a carboxyl group through electrophilic substitution. The mechanism for the reaction can be summarized
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SYNTHESIS AND CHARACTERIZATION OF POLYANILINE/POLY (P-HYDROXYANILINE)/Fe3O4 MAGNETIC NANOCOMPOSITE M. R. SABOKTAKIN‚ A. M. MAHARRAMOV‚ M. A. RAMAZANOV Baku State University‚ Baku‚ Azarbaijan E-mail: mamed_r50@mail.ru Several composites have been studied for static dissipationand microwave absorbing materials based on polyaniline with metallic oxides. These composites which are conducting polymers have been widely used because of their lower density as well their good environmental stability as in
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Jennie K. Daniels Organic Chemistry 2121 11 February 2014 Synthesis of Aspirin Salicylic acid derivatives‚ or salicin‚ are found in the bark of the willow tree. In the 5th century B.C.‚ Hippocrates ground the bark into a powder‚ and later‚ the Natives Americans chewed on the bark to alleviate fever and pain1. In the 19th century‚ a German chemist by the name of Felix Hoffman wanted to find a medication that would ease
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Abstract Introduction The acylation of the α carbon position of a carbonyl group is one of the greatest breakthroughs that has benefited chemists in organic synthesis particularly when in need of building a carbon skeleton of interest in a molecule. For one to be able perform this acylation technique‚ there are two mar approaches which are employable. The first method involves the deprotonation of the α-Carbon atom which has a pKa known to be ̴20 through the use of a strong base for instance
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