Synthesis of Aspirin Learning Goals 1. To synthesize aspirin from salicylic acid and acetic anhydride. 2. To purify the crude product by Recrystallization. Introduction Most drugs are chemical compounds which are described as "organic compounds" because they are comprised primarily of the elements carbon‚ hydrogen and oxygen. The present experiment will be the synthesis of a familiar organic compound called aspirin. The common chemical name is acetylsalicylic acid. Aspirin‚ the
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Introduction: The purpose of this lab was to learn how to use salicylic acid to make aspirin. Aspirin is the most widely used over-the-counter drug in the world. The average tablet contains about 325 milligrams of acetylsalicylic acid with an inert binding material such as starch. Aspirin is used to relieve pain‚ reduce inflammation‚ and lower fever. Aspirin originally was derived by boiling the bark of the white willow tree. Although the salicin in willow bark has analgesic properties‚ purified
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EXERCISE 11 SYNTHESIS OF ASPIRIN MARAVILLA‚ Ana Mikaela B Group 4 CHEM 40.1 1L Date performed: September 30‚ 2013 Date submitted: October 7‚ 2013 VI. RESULTS AND DISCUSSION Aspirin is prepared by the esterification of salicylic acid with acetic anhydride under acidic conditions. The phenol group in salicylic acid is replaced by a carboxyl group through electrophilic substitution. The mechanism for the reaction can be summarized
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Experiment 2 and 3: Synthesis of Aspirin and Determination of Melting Point A. Abstract Aspirin is the common name for the compound acetylsalicylic acid‚ widely used as a fever reducer and as a pain killer. The first part of the experiment aims to synthesize aspirin from the reaction of salicylic acid with acetic anhydride with the aid of phosphoric acid as a catalyst. The second part of the experiment aims to assess the purity of aspirin through the determination of its melting point and
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LIDE Learning Center‚ Inc. 6539 Isabel‚ Leyte Synthesis of Aspirin An Investigatory Project Presented to: Edmundo A. Quiñones Chemistry Teacher In Partial Fulfillment of the Requirements In Science and Technology III (Chemistry) Presented by: Kenneth Ivan P. Durano Cyrill Val G. Lozano March 6‚ 2010 APPROVAL SHEET This investigatory project entitled “The Synthesis of Aspirin” requirement for Science and Technology III (Chemistry) has
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Experimental Synthesis of Aspirin and Melting Point Purity Analysis Donald Yeargin CH 222‚ Section 24221 Department of Chemistry Portland Community College Portland‚ OR Abstract The various methods available to synthesize aspirin lead to the need to examine and evaluate production efficiency and purity. The purpose of our experiment was to synthesize acetyl salicylic acid (aspirin) and then determine the relative purity of the synthesized sample by observing the melting point temperature
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Introduction Table of Contents Introduction Materials Chemicals Equipment Safety Containers Measuring Devices Other Equipment Procedure Synthesis of Aspirin Crystalizing the Aspirin Recrystallizing the Crude Aspirin Finding the Melting Point Range Safety Precautions Acetic Anhydride Sulphuric and Salicylic Acid Heating Observations Mass of Aspirin Synthesized Melting Point Calculations Percentage Yield Maximum Yield Crude Product Final Product Melting Range Percentage Error
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this lab was to synthesize and purify aspirin. The theoretical yield was calculated to 3.766g. The actual yield of pure aspirin was 2.863g with a yield of 76%. The percent yield indicates that our synthesis was a success but the yield is low and indicates that some of the aspirin was lost during synthesis. Some reasons for loss can result from human error such as loosing product from sticking on the spatula and the Buchner funnel and several weighings. Also‚ when transferring the crude aspirin into
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Organic Synthesis of Aspirin Abstract The purpose of this experiment is to synthesize a common organic product called acetylsalicylic acid (aspirin)‚ and to become familiar with the optimum conditions needed for successful yields. Aspirin is produced from an acid catalyzed reaction between salicylic acid with acetic anhydride. The crystalline aspirin is synthesized and purified by recrystallization‚ although there is not a hundred percent yield due to sources of error. Introduction Aspirin is a
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Preparation of an Ester Acetylsalicylic Acid (Aspirin) OBJECTIVE: To become familiar with the techniques and principle of esterification. DISCUSSION: Aspirin is a drug widely used as an antipyretic agent (to reduce fever)‚ as an analgesic agent (to reduce pain)‚ and/or as an anti-inflammatory agent (to reduce redness‚ heat or swelling in tissues). Chemically‚ aspirin is an ester. Esters are the products of reaction of acids with alcohols‚ as shown in the following equation using
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