Figure 6: Imatinib The first imatinib drug synthesis was done by Zimmermann (figure 7) in 1993‚ he used a chain of the reaction to reach to imatinib but the important part is that both guanidinium nitrate 7 and aminopyrimidine 8 are precipitated from the respective reaction mixtures by the addition of Figure 7: imatinib synthesis by Zimmermann insolubilizing solvents‚ so we got a condensation reaction between guanidinium salt 7 with enone “9” to form the aminopyrimidine “8” then “8” is
Premium Protein DNA Amino acid
When studying theodicies you can find that some are extremely intellectual‚ while others can be more practically applied to evil. The N.T. Wright and the Problem of Evil theodicy is somewhere in between the scale of extremes. N.T. Wright takes studies from the Bible to answer questions of Gods involvement of evil and gives Christians a way for them to be active as well. When N.T. Wright was forming his theodicy it is obvious he spent a lot of his time in the scriptures for answers. Wright would
Premium Jesus Problem of evil Bible
Synthesis of Benzoin Date of Experiment: 1-26-15 Chelsea Price Lab Partner: Joey Simmons Abstract: In this experiment‚ benzoin was synthesized from benzaldehyde‚ using thiamine hydrochloric acid as a catalyst. The thiamine HCl was deprotonated by sodium hydroxide and acted as a nucleophile to attack the benzaldehyde. A water-cooled condenser was used to heat the solution at reflux. Vacuum filtration was used to wash and dry the product. The benzoin product was recrystallized
Premium Chemistry Alcohol Water
In the last experiment‚ aspirin was synthesized followed by characterization of the product using several different techniques. Melting point was a test that provided information about the identity and purity of the aspirin product. The iron(III)chloride test was used to detect the presence of a phenol group‚ with a positive result indicating the reactant salicylic acid was leftover as an impurity. Thin layer chromatography (TLC) was also used to determine if the white powder synthesized
Premium Aspirin Salicylic acid Acetic acid
Multistep Synthesis of Benzilic Acid The synthesis of several complex organic compounds follows a multistep synthesis. "Multistep synthesis" refers to the procedure in which the product of one reaction serves as the starting material in the subsequent reaction. The multistep synthesis of benzilic acid begins with a conversion benzaldehyde to benzoin through a condensation reaction. The benzoin then oxidizes into benzil‚ which undergoes rearrangement to give benzilic acid. Benzoin Synthesis * When
Premium Chemical reaction Chemistry Alcohol
As shown in the balanced chemical reaction in figure 1‚ Felbinac is synthesized from 4-bromophenyl acetic acid‚ phenylboronic acid‚ and 10% Pd/C. Figure 1: The balanced chemical reaction showing the synthesis of felbinac. It functions by inhibiting cyclooxygenase-1‚ which releases prostaglandins that cause pain as a response to injury. In a study conducted by Moore et al.‚ 160 patients were subject to various topical NSAIDS to determine their effectiveness
Premium Oxygen Carbon Carbon dioxide
Our data displayed supports the notion that by increasing the acidity of the catalyst‚ the production of aspirin will increase. Our hypothesis was proven correct. In our data‚ we calculated the percent yield and percent error of each trial. We also calculated the average of the percent yields and the percent errors of each catalyst. In the end‚ we saw that for the sulphuric acid catalyzed aspirin‚ we saw an average of 69.7% percent yield and an average 30.3% percent error. As for the phosphoric acid
Premium Aspirin Salicylic acid Acetic acid
ineffective. In order to help resolve the crisis‚ antibiotics were found through screenings of soil microorganisms. However‚ soil microorganism’s antibiotics were depleted by the 1960s and their antibiotic effects were unable to be replicated through synthesis. In this experiment‚ the researchers developed numerous methods to cultivate uncultured organisms in their environment. The goal of this experiment was to find antimicrobials in the uncultured soil. Through this successful experiment‚ the researchers
Premium Bacteria Antibiotic resistance Microorganism
1X TBE buffer was added to fill in wells‚ to create a smooth buffer surface. Using a micropipette 25 µL of my dye sample mix was added to the well. The gel was run at 130 V for 30 minutes. The gel was stained for 10 to 15 minutes using ethidium bromide. The gel was viewed using UV transillumination and a photograph was taken of the gel. Analysis of Genotype and Allele Frequency In Whole-Class Data Each student’s genotype of +/+‚ +/-‚ and -/- were counted and put into a genotype frequency equation
Premium DNA Gene Genetics
IDE COMPARITIVE STUDY ON QUALITY OF SERVICES IN ORGANIZED RETAIL OUTLETS (A study on Big Bazaar and CMR Shopping Mall of Visakhapatnam‚ Andhra Pradesh) Prof. Pulidindi Venugopal M.B.A.‚ Ph.D. VIT Business School VIT University. Vellore – 632 014 Ph. No. 9025555062 E-mail: pulidindi_2002@yahoo.com Geetha Singee Shatakshi Dhawan MBA (Int.) VIT Business School VIT UNIVERSITY COMPARITIVE STUDY ON QUALITY OF SERVICES
Premium Retailing Shopping mall