Synthesis of Aspirin Name: Xuanyi Li Teaching assistant: Deirdre Zwilling November 15‚ 2009 Purpose: To synthesize aspirin‚ a common analgesic drug‚ via nucleophilic acid-catalyzed substitution reaction of salicyclic acid with acetic anhydride. The whole reaction is catalyzed by phosphoric acid. (The experiment involved three parts: The synthesis of aspirin‚ the isolation and purification of aspirin‚ and the estimation of the purity of the final product.) [pic] Procedure[1]: A mixture
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Purity of Aspirin Objectives - To research‚ using various sources‚ the history of aspirin‚ its use in medicine‚ methods of synthesizing it and of measuring its purity - To compare the % purity of a branded aspirin tablet with a generic aspirin tablet - To compare 2 methods of composition analysis of the two types of aspirin Research
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Potentiometric Titrations Accuracy The accuracy of a potentiometric analysis is limited by the measurement error for the cell’s potential. Several factors contribute to this measurement error‚ including the contribution to the potential from interfering ions‚ the finite current drawn through the cell while measuring the potential‚ differences in the analyte’s activity coefficient in the sample and standard solutions‚ and liquid junction potentials. Errors in accuracy due to interfering ions
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Dissociation Model of Prejudice suggests that processing information about others occurs in two-step: the first step triggers the stereotypes automatically‚ and the second step is that people have the control whether to accept the stereotype or not. By this theory‚ people cannot control the acceptances of the stereotype if they are distracted or not paying attention. Dissociation Model gives a cognitive explanation of the source of being
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Lab Report Synthesis and Characterization of Aspirin (Acetylsalicylic Acid) The Synthesis and Characterization of Aspirin (Acetylsalicylic Acid). Summary: In this experiment‚ we produced 4.21 g of acetylsalicylic acid. Our theoretical yield was calculated to be 5.22 g. Therefore our % yield was determined to be 80.6%. The experimental boiling point range of acetylsalicylic acid was found to be 130-132° C. The true melting point of acetylsalicylic acid is 135° C‚ therefore our percent
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Jeana Greaves Chem3301-112 June 19‚ 2013 Synthesis of Aspirin from Methyl Salicylate Introduction The synthesis of Aspirin (Acetyl Salicyclic Acid) began with methyl salicylate and sodium hydroxide as the reagent. The polar oxygen accepts the electrons from now positively charged hydrogen. The positively charged sodium disassociates leaving the hydroxide ion with a negative Scheme 1 shows the mechanisms that were demonstrated during the synthesis of Aspirin. charge that attracts to the positively
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Jennie K. Daniels Organic Chemistry 2121 11 February 2014 Synthesis of Aspirin Salicylic acid derivatives‚ or salicin‚ are found in the bark of the willow tree. In the 5th century B.C.‚ Hippocrates ground the bark into a powder‚ and later‚ the Natives Americans chewed on the bark to alleviate fever and pain1. In the 19th century‚ a German chemist by the name of Felix Hoffman wanted to find a medication that would ease
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and silver deserve to have their integrity as unique substances respected‚ so do humans understandably try to uphold the purity of their given inclinations and values. Sectarian paths of all kinds come from this need to uphold congruency‚ and our many different schools of thought in both science and religion are the result. The price of purity is truth‚ however‚ for where purity demands homogeneity‚ truth contains multitudes. Whether we seek spiritual transcendence and deny our primitive biology
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isomers of α-phenylcinnamic acid. This was accomplished by refluxing benzaldehyde‚ phenylacetic acid‚ acetic anhydride and triethylamine as a base. The chemical equation of a Perkin Reaction can be seen below. The reaction mechanism for the synthesis of α-phenylcinnamic acid is shown below: Results: Theoretical Yield Therefore‚ phenylacetic acid is the limiting reagent. Table 1. Literature and actual IR values of (E) and (Z) isomers of α-phenylcinnamic acid. Compound Literature
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Abigail Haymon October 14‚ 2013 EN 101 D Essay #2 Purity Over Lust The worst thing that happened to a friend in high school that could have been prevented was her pregnancy. As a Christian‚ purity should have been an important aspect in her life; unfortunately she had a different mindset. It all started with a boy she met at a party. This boy that she met did not have the same values that she had‚ such as her Christian faith. That should have immediately caught her attention and been a major
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