18‚ 733-766 733 New Lead Structures in Antifungal Drug Discovery Chunquan Sheng and Wannian Zhang* Department of Medicinal Chemistry‚ School of Pharmacy‚ Second Military Medical University‚ 325 Guohe Road‚ Shanghai 200433‚ People’s Republic of China Abstract: During the past two decades‚ the incidence of invasive fungal infections has been increasing dramatically. Clinical available antifungal agents have several drawbacks such as limited potency and spectrum‚ drug related toxicity‚ non-optimal
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Drugs and Driving Injuries‚ especially from motor vehicle collisions‚ are the leading cause of death for individuals under age 44. The presence of alcohol is the factor most frequently associated with fatalities in vehicles‚ drownings‚ falls‚ and fire (U.S. Department of Health and Human Services‚ 1987). In the first report to Congress on traffic safety and alcohol (U.S. Department of Transportation‚ 1968)‚ it was concluded that more than 50 percent of fatal traffic collisions and 33 percent of
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Effects of Drugs The Effects of Marijuana‚ Cocaine‚ and Methamphetamine on American Society Topic: The Effects of Marijuana‚ Cocaine‚ and Methamphetamine on American Society. Thesis: The effects of illegal drug use of marijuana‚ cocaine‚ and methamphetamine on American society. I. Illegal drug use A. History B. Effects C. Problems II. Three types of drugs A. Marijuana B. Cocaine C. Methamphetamine III. Effects and Treatments of the Three types of drugs A. Short
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Name of Drug | | Mechanism of Action | Indication | Adverse Effect | Special Consideration | Nursing Responsibility | Rationale | Generic Name:AcetylcysteineBrand Name:(Fluimucil)Classification:MucolyticAntidote | Dosage:200mgFrequency:Route:Oral (diluted in ½ glass of water) | Splits links in the mucoprotein contained in respiratory mucus secretion‚ decreasing the viscosity of the mucus. | Mucolytic adjuvant theraphy for abnormal‚ viscid or inspissated mucus secretion in acute and chronic bronchopulmonary
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Drugs In Sport Today I will be talking about how drugs in sport are immoral and a bad influence on younger generations. Drugs in sport is one of today’s most controversial issues in our daily lives. Such as the Essendon drug scandal‚ Lance Armstrong and many‚ many more have suffered having the punishments that come with taking drugs. Sport is meant to be a very enjoyable activity‚ but now with the shadow of drugs looming over it‚ sport has become very tedious. The real point of sport is
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Drugs: Good or Bad Imagine a world where drugs are legal‚ walking down the street and seeing people on drugs everywhere. Where almost everyone is going into convenient stores buying crack‚ marijuana‚ or even heroin. What kind of world would this be‚ to see junkies on the side of the road and it is perfectly legal. To see more crime than ever before from people who are trying to steal‚ kill‚ and rob just to get a fix. Believe it or not‚ but at one point all drugs were
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FACTORS AFFECTING DRUG ACTION In drug administration‚ many factors affect the action of the medication. These factors also affect the dose to be administered. The usual adult dose of medication as listed in standard references‚ is based on the assumption that the adult weighs 150 pounds‚ but since the following variables influence the action of the medication‚ they also may alter the quantity of the drug necessary to produce the desired results a. Weight. Heavy‚ burly clients require larger doses
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Drug Addiction Drug addiction is a problem that has been increasing immensely among our society today. Drug addictions can only hinder or restrain us from accomplishing goals or dreams in life. People sometimes feel they are too bright‚ too powerful‚ too much in control to become addictive. Addiction can trap anyone. It can lead to harming ones body‚ causing problems in family structure‚ and contribute to the delinquency in society. The sooner people seek help for drug addiction problems‚ the more
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Drug Obsession Most teenagers tend to want to try new things because it’s shown on TV in a cool or unique way. Drugs are a popular topic for TV shows‚ movies‚ music‚ and music videos for this generation. TV shows‚ movies‚ and music show that it’s okay to do and or sell illegal substances clearly this is wrong. Showing drugs in this capacity give the illusion that it’s okay to take or do them. This makes teenagers assume that it is alright to take the substance even though it is not. Drug
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Mark Mark of New Jersey is one of the drug addicts I chose to talk to. He is my uncle and I have had a very close relationship with him throughout my whole life. He is currently 54 years old and has been drinking since he was in his twenties. He states that is was only socially until he was about 45. During this year he fell off a ladder and tore is shoulder and needed surgery. He owns his own construction company so he was hesitant to take the time off to have the surgery. He was in a great deal
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