Lovenox was created in 1993 and approved in 12/30/1998. It was created initially at Rhone-Poulence Rorer Pharmaceutical Inc. Enoxaparin‚ the generic name for Lovenox‚ is a complex mixture of Oligosaccharides that vary in chemical structure and size. Oligosaccharides are carbohydrates whose molecules are composed of relatively small numbers of monosaccharide units. It is made up of heparin by chemically breaking up the larger heparin chains into smaller fragments. The qualities of the heparin and
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localized pain. Later‚ what appears to be bruising occurs‚ but this is the fat and muscle beginning to necrotize. As the infection and necrosis spread throughout the fascial layers‚ vasoconstriction (decrease in the caliber of blood vessels) and thrombosis (formation of a blood clot) lead to edema (swelling caused by fluid in the tissue) and further diminish circulation‚ resulting in hypoxemia (deficient oxygenation of the blood) and necrosis (state of death) of the fascia‚ skin‚ soft tissue‚ and
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vasoconstriction by direct action on the muscles of the arterioles‚ and repeated dosages injure the vascular endothelium. These actions initially reduce blood flow and eventually lead to complete stasis with terminal necrosis of the extremities due to thrombosis. A cold environment predisposes the extremities to gangrene. In addition‚ ergot has a potent oxytocic action and also causes stimulation of the CNS‚ followed by depression. Ergot alkaloids inhibit pituitary release of prolactin in many mammalian
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and physicians alike. However‚ the majority of parents are unaware of the dangers when combining NHP’s with various medications. Young critically ill children with chronic conditions influencing dynamic blood flow such as central line related thrombosis or cardiac surgeries needing long-term anticoagulation therapy are being prescribed Warfarin. Warfarin is an agent that is commonly prescribed to prevent clot formation and extensions (Bauman‚ 2012). When prescribed warfarin physicians should
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an unexpected result. Previous studies have shown that the instability of the atheromatic plaques comes with higher cellularity (22‚ 23). Tracy et al proved that higher cellularity is associated with instable lesions and Gordon et al that acute thrombosis was associated with higher proliferation rate (22‚ 23). Lastly‚ Moreno et al focused on the thrombogenicity of SMC and tissue factor’s expressed by MC (24). The small number of patients included in our study may explain these contradicting results
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Introduction Fibromuscular dysplasia (FMD) is currently defined as an idiopathic‚ segmental‚ non-inflammatory and non-atherosclerotic disease of the musculature of arterial walls‚ leading to stenosis of small and medium-sized arteries.[1] The prevalence of FMD is not precisely known. Several studies determined prevalence in arteriograms of potential kidney donors. Craig et al reviewed the results of 1‚862 renal angiograms obtained in potential renal donors and found FMD in 71 patient (3.8%).[2]
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Cited: * Breathing. Somax Sports.‚ 2012. Web. 18 November 2012. * Deep Vein Thrombosis/Pulmonary Embolism (VT/PE). Centers for Disease Control and Prevention.‚ 2012. Web. 18 November 2012. * “Diabetes.” Complementary Medicine. University of Maryland Medical Maryland.‚ 2011. Web. 19 November 2012. * “Donor Stem Cells Just As Good
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Abstract The subject of evidence-based practice is discussed in this paper beginning with a definition of the term taken from our text by Blais and Hayes (2011). I discuss the way in which we care for intravenous lines as an example of a procedure done at our hospital that uses evidence-based guidelines like those listed on the National Guideline Clearinghouse website to reduce central line associated blood stream infections. A summary of an article demonstrating the use of a solution of chlorhexidine
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Case Study 5: Cerebrovascular Accident Situation: It is early morning and the client‚ an 80-year-old woman‚ is getting out of bed. She has a mild headache over the right temple‚ is fatigued‚ and feels slightly weak. She calls for her husband to let him know she will be going back to bed for a while. When her husband comes in to check on her‚ he finds that she is having trouble saying words and has a slight left-sided facial droop. When he helps her up from the bedside‚ he notices weakness in her
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illness. Everyone has known for years that aspirin is a fast and reliable painkiller that also reduces inflammation and cools fevers. More recently it has become just as well known as a help to people with heart complaints such as angina‚ coronary thrombosis and after coronary bypass surgery. It is becoming better known‚ too‚ in prevention of stroke. Among other diseases in which active research about aspirin is showing great promise - and in which it is now being increasingly used - are toxemia of
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