Graves’ disease is an autoimmune disease. It most commonly affects the thyroid‚ frequently causing it to enlarge to twice its size or more (goitre)‚ become overactive‚ with relatedhyperthyroid symptoms such as increased heartbeat‚ muscle weakness‚ disturbed sleep‚ and irritability. It can also affect the eyes‚ causing bulging eyes (proptosis). It affects other systems of the body‚ including the skin‚ heart‚ circulation and nervous system. It affects up to 2% of the female population‚ sometimes appears
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and different treatment options available for hyperthyroidism. In healthy people‚ the thyroid makes just the right amounts of two hormones‚ T4 and T3‚ which have important actions throughout the body. These hormones regulate many aspects of our metabolism‚ eventually affecting how many calories we burn‚ how warm we feel‚ and how much we weigh. In short‚ the thyroid "runs" our metabolism. These hormones also have direct
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abnormal thyroid growth however‚ the most common cause of goiters is due to iodine deficiency and cases are more common in developing countries due to the lack of iodine in diets. Iodine is extremely important in thyroid function because it is used in thyroid hormone production. Goiters are more closely associated with Hashimoto’s disease since TSH stimulation causes the thyroid to grow. In some cases‚ goiters can be associated with hyperthyroidism‚ such as Grave’s Disease depending on thyroid hormone
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result of an overactive thyroid hormone usually resulting from an enlarged thyroid gland‚ and it is most common in older cats. While it does occur in younger cats‚ it is a rare occurrence as only about 5% of cases are from younger cats. [4] The enlargement of the thyroid gland is typically the result of a non-cancerous tumor located in the gland. The thyroid hormone (T3 and T4) is produced in the two thyroid glands in the neck on either side of the trachea. The thyroid hormone regulates metabolism
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disease an immunological disorder that affects about 3 % of the population & almost 10 million people just in the United States. It is a condition where your immune system makes an antibody called TSI or thyroid stimulating immunoglobulin this causes the thyroid gland to generate too much thyroid hormone. There are many factors that play a role when someone gets Grave’ disease. There are some people that are just predisposed to Graves’ disease because of their genes‚ our gender also plays a role & women
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tissues and organs. The thyroid gland‚ which is a part of the endocrine system‚ releases a hormone that maintains metabolism. This hormone is thyroxine. Thyroxine production is controlled by thyroid stimulating hormone‚ which is released by the pituitary gland. TSH stimulates the thyroid gland to produce thyroxine. In this experiment‚ the effects of TSH and thyoxine on metabolic rate are investigated. Hypothesis: With the information given‚ we tested the effects of given hormones on the body by using
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the thyroid gland. The body makes antibodies that bind to TSHR‚ thyroid- stimulating receptor‚ on the thyroid gland. This leads to hyperthyroidism or a huge increase in the release of hormones from the thyroid gland. Under normal conditions TSH or thyroid stimulating hormone‚ released from the anterior pituitary gland‚ mediates the release of thyroid hormone. This cycle of the production of thyroid hormone is self- regulated by a negative feedback system: an increase in the release of thyroid hormones
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Actions of Thyroid Hormone and Mechanism of Graves’ Disease Thyroid hormones are capable of acting at nearly every organ system in the human body. They promote bone formation‚ increase basal metabolic rate‚ heat production‚ oxygen consumption‚ and they alter the cardiovascular and respiratory systems resulting in an increased blood flow and oxygen delivery to the tissues. A quick summary of thyroid hormone synthesis‚ taken directly from the Kopp article‚ is included at the end of this learning
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Hypothyroidism Normally‚ the thyroid-stimulating hormone (TSH) is produced when the hypothalamus excretes thyrotropin-releasing hormone (TRH). The secretion of TRH triggers the pituitary gland to release TSH. TSH then activates a release of triiodothyronine (T3) and thyroxine (T4)‚ controlling the body’s metabolism. When T3 and T4 levels rise‚ the secretion of TRH and TSH decrease. When thyroid hormone levels decline‚ there is an increase in TRH and TSH secretion (Buttaro‚ Trybulski‚ Bailey‚ & Sandberg-Cook
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Hyperthyroidism‚ also known as Thyrotoxicosis‚ is a condition that is caused by the excessive release of thyroid hormones into the body. These thyroid hormones include thyroxine and triiodothyronine. Hyperthyroidism‚ while not a deadly disease‚ effects about 1.2% of the population‚ occurs mostly in women‚ and can have detrimental effects on the body. Generally‚ Hyperthyroidism arises as a symptom of other more prevalent diseases. An example of this is Graves disease. Graves disease is the number
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