heart attacks f) Merck blamed naproxen for skewing the results against Vioxx 3) New England Journal of Medicine Omission g) Merck omits three heart attacks from article submission h) Inclusion of omitted data caused a significantly greater result 4) FDA Reaction i) Letter regarding downplay of risks j) Addition of warning label to Vioxx k) Additional study results 5) Approve Study l) Results with placebo group cause Merck to recall drug
Premium Coronary artery disease Aspirin Hypertension
TO: Dr. Roy Vagelos‚ Chairman and CEO Merck Corporation. January‚ 1991. The decision to move forward with the program to donate the new drug Mectizan on a large scale to the affected population in the Third World needs to be systematically analyzed. There are two especially important angles from which this decision needs to be considered. The first concern that needs to be taken into account is that of the stockholders and investors in this company‚ whose interests you are ultimately charged with
Premium Medicine Pharmacology Pharmacy
1. How has Merck been able to achieve substantial returns to capital given the large costs and lengthy time to develop drugs? Merck had a 14% increase in sales between 1997 and 1998 and 22% increase in sales from 1998 – 1999‚ and a 13% annual increase in earnings over the same period. Merck’s business strategy consists of two parts: (1) developing and marketing new drugs through internal research‚ and (2) developing partnerships with smaller biotechnology companies. Since 1995‚ Merck had launched
Premium Expected value License Money
including Bayer AG and Novartis are exploring a deal for Merck & Co Inc’s consumer healthcare business‚ as they seek to gain scale in a fragmented industry‚ according to several people familiar with the matter. Reckitt Benckiser Group PLC and Procter & Gamble Co are also among the parties that have held discussions with Merck about buying the unit‚ best known for Coppertone sunscreen and Claritin allergy medicine‚ the sources said this week. The Merck business‚ which also includes Dr. Scholl’s foot
Premium Pharmacology Marketing Pharmacy
Pharmaceuticals: Merck Sustaining Long-term Advantage Through Information Technology Hiroshi Amari Working Paper No. 161 Working Paper Series Center on Japanese Economy and Business Columbia Business School December 1998 Columbia-Yale Project: Use of Software to Achieve Competitive Advantage PHARMACEUTICALS: MERCK Sustaining Long-term Advantage Through Information Technology Prepared by Hiroshi Amari Research Associate‚ Yale University William V. Rapp and Hugh T. Patrick Co-principal
Premium Clinical trial Pharmaceutical industry Drug development
c. Moody’s Investors Service downgraded the long-term senior unsecured rating of AZN from A1 to Aa2 in 2007. Assess any potential association between this downgrade and AZN’s arrangements with Merck. Paris‚ July 30‚ 2007 -- Moody’s Investors Service downgraded the long-term senior unsecured ratings of AstraZeneca plc and its guaranteed subsidiary to A1 from Aa2. This downgrade followed the announcement of AstraZeneca’s acquisition of MedImmune for a total consideration of more than US$15 billion
Premium Money
Complete the following 2 exercises 1. Write checks to pay the following bills. The beginning balance in the checkbook is $4562.79. NOTE: The checks are setup for you to manually type the necessary information to successfully complete the assignment. A. Write check #5648 to the American Medical Association for $356.00 for new coding books. B. Write Check #5649 to the Blackburn Utility Company for $46.90 to pay the water bill. C. Write a check for the office mortgage payment to First
Premium Cheque Money English-language films
The pursuit of excellence 1) Socrates did not write "Apology". Socrates did not actually write anything‚ It was his friend Plato that wrote and documented Socrates’s speeches and dialogs. The "Apology" supposes to be an accurate account by Plato of Socrates’s trial before the Athenian jury in 399BCE. The trial began with the prosecutors presenting their case against Socrates before the Athenian jury. In this trial Meletus‚ the prosecutor‚ argued that Socrates was guilty of corrupting the youth
Premium Epic of Gilgamesh Personal life
and enjoys a good and sustainable market’. Business excellence is often characterized by principles‚ practices and techniques in managing the organisation and achieving results‚ based on a set of fundamental concepts or values. Many countries have developed their own models and frameworks to evaluate and recognize organizations for their efforts in business excellence through awards programmes. In Singapore‚ for example‚ the Business Excellence (BE) initiative was started by Spring Singapore to assist
Premium Management PDCA
Merck and Co. and river blindness MANUEL VELASQUEZ‚ Business Ethics. Concepts and cases 4th edt.‚ Prentice Hall‚ Upper Saddle River‚ New Jersey‚ 1998 River blindness is an agonizing disease that affects some 18 million impoverished people living in remote villages along the banks of rivers in tropical regions of Africa and Latin America. The disease is caused by a tiny parasitic worm that is passed from person to person by the bite of the black fly which breeds in river waters. The tiny worms
Premium Pharmaceutical industry Ethics Drug discovery