Chapter 33 notes: Intrinsic cellular defense against virus infection 1. Toll- like receptors sense virus infections a. Toll-like receptors (TRL) i. Located on the cell surface or in endosomal membranes = recognize conserved structures found in pathogens ii. Highly conserved receptors from flies humans iii. Most mammals have between 10-15 (humans = 10) iv. TLR – 2: lipoproteins/glycoproteins (mealsels‚ hepB‚ herpes) v. TLR– 3: dsRNA (west
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animallike and funguslike. A virus is a microscopic particles that make up either DNA or RNA core covered by a protein coat. Viruses are so small an electrn microscope is needed to see them. Viruses are not classified in any kingdom because they are not cells. They show almost none of the characteristics of living things. The classification of viruses are based on it’s shape‚ the kind of nucleic acid it contains‚ and the type of organism the virus infects. The protein coat of a virus gives the particle it’s
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Varicella zoster virus is a double stranded icosahedral‚ nucleocapsid DNA molecule‚ with a lipid envelope enclosing it. Varicella zoster virus develops a latent infection in the neurons of the sensory ganglia. Primary infection causes varicella (chickenpox)‚ and reactivation of the virus causes a latent infection known as herpes zoster (shingles). Varicella is more common in children. Infection in adults is more severe and can lead to interstitial pneumonia. It is also more frequent in immunocompromised
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A bacteriophage (informally‚ phage) is a virus that infects and replicates within bacteria. The term is derived from ’bacteria’ and the Greek φαγεῖν phagein "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome‚ and may have relatively simple or elaborate structures. Their genomes may encode as few as four genes‚ and as many as hundreds of genes. Phage replicate within bacteria following the injection of their genome into the cytoplasm. Bacteriophage are among
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Modeling the Course of a Viral Illness and its Treatment Math Internal Assessment Student: Xu‚Dejing(Charlotte) Session number:001762023 Date: March 26‚ 2010 I. Introduction: When viral particles of a certain virus enter the human body‚ they replicate rapidly. In about four hours‚ the number of viral particles has doubled. The immune system does not respond until there are about 1 million viral particles in the body. The first response of the immune system is fever. The rise in temperature
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factors govern the severity of JEV pathogenesis. The failure of the host to produce antibodies against the virus is associated with an increased likelihood of the disease to turn lethal (Ghosh D‚ 2009). An important factor in the increase of pathogenesis is crossing the blood –brain barrier and this result in neurotropic viral infection. After entering the body through a mosquito bite‚ the virus reaches the central nervous system (CNS) via leukocytes where JEV virions bind to the endothelial surface
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Melissa Babajko Microbiology 214BA Dr. May June 6‚ 2012 Staphylococcus aureus- Is a facultative anaerobic‚ Gram-positive‚ salt positive‚ cocci shaped bacterium. Staphylococcus aureus is found as normal part of the skin floral in the nasal passages and on the skin. An estimated twenty percent of people naturally have harmless Staphylococcus aureus on their skin and are long-term carries for Staphylococcus aureus. Staphylococcus aureus is the most common strand of Staphylococcus in humans to date
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com/story/148375/student-wont-be-deported-for-spying-on-gay-roomie.html) 2. Virus A virus (from the Latin virus meaning toxin or poison) is a small infectious agent that can replicate only inside the cells of other organisms. Viruses are too small to be seen directly with alight microscope. Viruses infect all types of organisms‚ from animals and plants to bacteria and archaea. [1] Since the initial discovery of tobacco mosaic virus by Martinus Beijerinck
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The common cold is not just one virus‚ but over 200 different strains of viruses. The most common type of cold-causing virus is the rhinovirus‚ causing 20% – 50% of all colds. It is widely believed that it is the virus itself that somehow causes the observed symptoms. However‚ this is not the case. When a cold infects the body (the nasal cavity and back of the throat‚ to be precise)‚ the white blood cells trigger chemical mediators to help fight the attack‚ indirectly causing symptoms such as a blocked
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food borne illnesses but the norovirus is very interesting. A norovirus is a small virus that contains RNA and is surrounded by a protein coating. Based on genetic typing‚ it is now known that there are at least twenty-five different strains if norovirus that affect humans. Norovirus infection is the most common cause of what some people call the “stomach flu‚” although norovirus is not related to the influenza virus. According to statistics from the CDC‚ there are twenty-one million cases of norovirus
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