complexation of agomelatine with HP β-CD to enhance aqueous solubility and then to its mucoadhesive tablet for buccal delivery of agomelatine. A major hurdle that has prevented the commercialization of many promising poorly soluble drug candidates is dissolution rate-limited bioavailability or permeation rate-limited bioavailability. Buccal route of administration provides better penetration of therapeutic and diagnostic agents‚ and a reduced risk in comparison to conventional treatments
Premium Pharmacology Morphine Opioid
DDT between beneficial and destructive Throughout the history‚ humans have faced a lot of problems‚ but the worst of all of these are the problems made by humans themselves. Every day we try to discover something new to help our society and to help us survive in the environment that we are living in. We use technology and chemicals as an example to come up with anything that can benefit us and realize its purpose. We started to have problems with mosquitoes‚ so scientists from all over the world
Premium Environmentalism Natural environment Human
Pros and cons of depend on tourism Today‚ many people spend almost all of their money on traveling around the world. Their expenditure makes a big income for many countries such as Caribbean‚ Egypt or Thailand. This is advantageous to the countries’ development; otherwise‚ tourism is impacting on these countries. Environmental pollution‚ destruction of monuments and dilution of culture are some problems that these countries’ government must solve if they depend solely on tourism revenues.
Premium Tourism Thailand Prostitution
Marissa Treece Theology 20611 11/13/08 Destruction of Marriage Much of today’s practicing adolescent population would argue the accusation false. As a whole‚ the liberal population would probably concur. But despite their continuously supported “pros” of premarital cohabitation‚ it is partly—and largely—responsible for the destruction of marriage as a sacrament and as an institution in America. In the following pages‚ I will address the sexual ethical issue of cohabitation prior to marriage. While
Premium Marriage
Pros and Cons of Nuclear Power What’s nuclear power’s biggest advantage? It doesn’t depend on fossil fuels and isn’t affected by fluctuating oil and gas prices. Coal and natural gas power plants emit carbon dioxide into the atmosphere‚ which contributes to climate change. With nuclear power plants‚ CO2 emissions are minimal. According to the Nuclear Energy Institute‚ the power produced by the world’s nuclear plants would normally produce 2 billion metric tons of CO2 per year if they depended on
Premium Nuclear power Uranium Nuclear fission
In the wake of the attacks on September 11‚ 2001‚ the United States faced many challenging decisions. The consequences of these decisions would shape the country from that day forward. However‚ there was one decision that made the rest infinitely simpler by providing information to key government officials. That was the decision to use Enhanced Interrogation Techniques (EITs) on those detained as suspected terrorists. EITs take many forms such as waterboarding‚ forced stress positions‚ and humiliation
Premium Central Intelligence Agency Torture George W. Bush
2000-2016 is 20‚145 and they are mostly males. Anyone at any age abuses it from 12 and older for at least once in their life time. In 2010 they had released a “abuse proof” OxyContin and it would make it much harder to crush and when it is mixed with water it turns to a jelly. So with it turning to a jelly it would make it much harder to inject it with a
Premium
Sudanese government‚ who are Arab Muslim‚ are going against the people in Darfur‚ who are Black Muslim. What the government‚ the Arab Muslims‚ are doing‚ is violating all human rights! They are ¨...burning villages‚ looting economic resources‚ polluting water sources‚ and murdering‚ raping‚ and torturing civilians.¨ (Mitchell Hamline School Of Law) This shows that the government has no mercy for the Darfurians‚ and will attempt to torture them as much as possible. Why is this still going on? The population
Premium Sudan Genocide
Proposition: Imagine that you are a 19-years old son of Turkish immigrants‚ returning from a trip abroad to German lands. The police detain you for unexplained reasons and next thing you know is that America pays your parole and you are later turned over to them. Your first encounter with America is not the statue of Liberty but Guantánamo detention camp where you spend your next five years being tortured by military officials and psychologists in inhumane ways. There are three main arguments of
Premium Torture Psychology Law
The respect of the filial piety within one’s home will affect everything; like a pebble creating ripples in the water. If we are benevolent within our home‚ we shall as well show Jen in other facets of life. Those who have the right to rule‚ as not all men are created equal should therefor exhibit Ren. With Ren‚ the ruler like the ripple effect of upholding the filial
Premium Ethics Philosophy Religion