there is lower than normal number of red blood cells or hemoglobin within a person‚ consequently decreasing the amount of oxygen being carried to the rest of the body. Causes of such a condition are usually insufficient amounts of iron‚ blood loss‚ lack of red blood cell production‚ or high rates of red blood cell destruction. (MNT‚ http://www.medicalnewstoday.com/articles/158800.php) One form of this condition is the disease Sickle Cell Anemia‚ an inherited blood disorder that affects hemoglobin. It
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Sickle cell anemia (SCA) is a genetic disorder that is hereditary. It affects the blood‚ and is caused when the hemoglobin in blood cells are deprived in oxygen from the proteins. These cause normal round blood cells‚ to have are rigid sickle shape. People affected by SCA have a higher risk of death‚ stroke‚ severe attacks‚ and severe rushes of pain. James Herrick discovered an anemia‚ and found bizarre sickle-shaped cells in 1910. A treatment for the disease was discovered in the 1920s by E. Vernon
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Sickle Cell anemia is a group of inherited red blood cell disorders‚ or a collection of recessive genetic disorders characterized by a hemoglobin variant called Hb S. Normal red blood cells are round like doughnuts‚ and they move through small blood tubes in the body to deliver oxygen. Sickle red blood cells become hard‚ sticky and shaped like sickles used to cut wheat. When these hard and pointed red cells go through the small blood tube‚ they clog the flow and break apart. This can cause pain‚
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Sickle Cell Disease (SCD) is a group of inherited red blood cell disorders. People with Sickle Cell Disease have abnormal hemoglobin‚ called hemoglobin S or sickle hemoglobin‚ in their red blood cells. People with SCD inherit two abnormal hemoglobin genes‚ one from each of their parents. One of these abnormal hemoglobin genes causes the production of hemoglobin S in the body.1 When a person has two hemoglobin S genes‚ Hemoglobin SS‚ this disease is called Sickle Cell Anemia.1 This is the most common
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WATER FLOW ACROSS CELL MEMBRANES pg. 1 Lab Report 1 Water Flow Across Semi-Permeable Membranes WATER FLOW ACROSS CELL MEMBRANES pg.2 WATER FLOW ACROSS CELL MEMBRANES The movement of water across semi-permeable membranes as it relates to the laws of thermodynamics and energy flow with the diffusion
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SICKLE CELL ANAEMIA Sickle cell anemia is an inherited condition. People with sickle cell anemia inherit two copies of the sickle cell gene‚ one from each parent. The sickle cell gene makes abnormal hemoglobin called Hemoglobin-S. The sickle cell gene is a trait due to a change in ONE nucleotide in the DNA sequence that leads to a change in ONE amino acid that changes how the hemoglobin protein folds. This change in the structure of the hemoglobin protein leads to a change in the shape of
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Sickle cell anemia was first discovered in the year of 1910. A young man by the name Walter Clement Noel from the island of Grenada‚ studied in Chicago. He went to Dr. James B. Herrick‚ whom was a cardiologist‚ with symptoms of anemia‚ who assigned Dr. Ernest Irons to the case. There Dr. Irons noticed that Noel’s red blood cells were the shape of a sickle. Although sickle cell anemia has occurred in Africa for thousands of years‚ Dr. Herrick was the first to provide a formal description of sickle
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Terminology 1 18‚ April 2013 Sickle Cell Anemia Sickle-cell Anemia is a genetic blood disorder caused by the presence of an abnormal form of hemoglobin molecules in which the red blood cells loose their disc-shape and become crescent shaped. The shape also known as “hemoglobin S”. unlike normal red cells which are usually smooth and malleable‚ tend to collect after releasing oxygen‚ and cannot squeeze through small blood vessels. The organs are then deprived of blood and oxygen. The basic life-span
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Introduction - sickle cell anemia The first suggestion that genes might provide the information for all proteins came from Linus Pauling’s lab at Caltech. He and his student Harvey Itano studied hemoglobin‚ the protein in red blood cells that transports oxygen from the lung to metabolically active tissues‚ like muscle‚ where it is needed. In particular‚ they focused on the hemoglobin of people with sickle-cell disease‚ also known as sickle-cell anemia‚ a genetic disorder common in Africans‚ and
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Case Study 97 1. Sickle cell disease is a group of disorders that affects hemoglobin‚ the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S‚ which can distort red blood cells into a sickle‚ or crescent‚ shape. SCD affects millions of people worldwide‚ particularly those with African‚ Spanish‚ Mediterranean‚ and Indian ancestry. Some 120‚000 infants are born with SCD every year worldwide
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