Aloe Vera is greatly useful in the treatment of gingivitis or periodontitis (17). It decreases inflammation, bleeding, and edema of the gingiva. It is a strong antibacterial in periodontal pockets where normal cleansing is challenging, and its antifungal properties help considerably in the difficulty of denture stomatitis (18) .also Aloe Vera is a possible anti-bacterial factor which is mentioned to be useful in fighting the microorganism and controlling periodontal disease (19). Vijayalakshmi .et al (2012). Demonstrated the in the Vitro inhibitory efficacy of Aloe Vera on MMP-9 (20). There is an increase in the use of conventional and chemical plaque control agents to prevent dental caries and periodontal disease. Various chemical mouthwashes are available in the market but are associated with side-effects like immediate hypersensitivity reactions, toxicity, tooth …show more content…
Other medicines may be developed from medicinal plants as these plants contain natural phytochemicals, and potentially can replace synthetic drugs (21, 22). Conventional non-surgical periodontal therapy is based on the elimination of foci of infections by mechanical debridement, including SRP, as well as local drug delivery (LDD) of therapeutic agents, such as herbal products into periodontal pockets. Use of medicinal herbs or their extracts is effective in preventing and treating oral conditions (23). Aloe Vera is an herbal plant, used in dentistry for the treatment of oral lichen planus (24), burning mouth syndrome (25), gingivitis (26) and periodontal diseases (27). Aloe Vera is a natural product contained in herbal dentifrices, which effect on the control of plaque and gingivitis. Aloe latex has Anthraquinones and enzymes like Brady kinase, which are chemical complexes that are used in healing and arresting pain because of their anti-inflammatory nature. Aloe Vera inhibits the cyclooxygenase pathway and reduces prostaglandin E2 production from