Children with positive HLA-B27 Reactive arthritis have more severe involvement and negative HLA-B27 does not rule out reactive arthritis.…
Osteoarthritis is a disease of the joints. It is one of the most common diseases nowadays. Unlike many other forms of arthritis, osteoarthritis does not affect other organs of the body. The most common symptom is pain in the affected joint after repetitive use.…
Osteoarthritis has to do with the loss of articular cartilage, the development of bony spurs at the joint margin, also known as osteophytes, it involves the inflammation of the synovial membrane and alterations to the subchondral bone. The order of which the changes in the bone, synovium and cartilage are influenced on the causes for osteoarthritis, these differ in each tissues effect on surrounding tissues. The pathophysiology of osteoarthritis has subtypes including inflammatory to a varying extent, pain due to tissue damage, and pain at rest.…
1) How are osteoarthritis and rheumatoid arthritis different? Osteoarthritis usually affects people 60 or older and is caused by increasing wear and tear at the joint surfaces or from genetic factors affecting collagen formation. On the other hand rheumatoid arthritis is an inflammatory condition. It is caused by the body attacking its own tissues as well as allergies, bacteria, viruses, and other genetic factors.…
There is no cure for rheumatoid arthritis, but there are a variety of treatments that can slow down the condition and keep joint damage at minimum. The earlier the treatment is started the more effective it is going to be.…
In 2005, an estimated 1.5 million or about 0.6 percent of the U.S. adult population had RA (NIAMS, 2009) and (CDC, 2012). Based on data from 1965-1990, it was found that people with RA are more than twice as likely to die than people of the same age in the general population (CDC, 2012). Rheumatoid arthritis is thought to be caused by a combination of genetic and environmental factors but at the present time there is no known cause of RA. Although, a definite cause is unknown, there are several known risk factors some which are considered modifiable (CDC, 2012). These include: family history, age, gender, reproductive/breastfeeding history and smoking.…
Joints - stiffness, pain, and swelling may commonly occur. Unlike rheumatoid arthritis however, permanent damage to the joints is almost unheard of.…
In his article featured in the global health magazine The Lancet, author Paul Creamer attempts to give an explanation of the causes and effects of osteoarthritis, which is one of the most common forms of arthritis to date. In his article Creamer describes the disease as “not a single disorder, but rather a group of overlapping distinct diseases” (Creamer, 1997, pg. 1) that are caused by both mechanical and biological events. Creamer claims that osteoarthritis “leads to a softening of the bone, fibrillation, ulceration, loss of articular cartilage, sclerosis and eburnation of subchondral bone” (Creamer, 1997, pg. 1) which can cause joint pain, morning stiffness, and loss of function in body parts containing the disease. There are a range of…
Arthritis is an inflammation of the joints. There are many types of arthritis. Some are more serious than other, and affect people in different ways.…
It occurs when the cartilage on the end of the bone begins wearing away, causing pain and stiffness. When the cartilage wears away completely, the bones rub directly against each other causing decreased mobility and chronic pain. Osteoarthritis is most common in people 50 and older, but it’s also prevalent in those with a family history of arthritis or lifestyles that add stress to the hip joints like athletes or laborers. Rheumatoid arthritis is when patients have damage to the hip joint from rheumatoid arthritis, or ankylosing spondylitis. Rhematoid arthritis actually is an autoimmune disease in which the synovial membrane becomes inflamed. The membrane then produces too much synovial fluid, damaging the articular cartilage. Traumatic arthritis could result from a fracture or infected hip. It’s the most common form of the disease. It sometimes results from a serious hip injury or fracture. The articular cartilage becomes damaged and over time causes hip pain and stiffness. The word “arthritis” means inflammation of the joint. Most people think of arthritis as the wearing away of cartilage in a joint. This is the end result of inflammation within a joint. Over a period of time, the inflammation can lead to cartilage loss and exposed bone, instead of a normal, smooth joint…
Genetics that are inherited from parents play a role into the formation of arthritis. The lifestyle of a person plays a role. Lifestyle plays a role in arthritis because not maintaining a healthy body weight applies extra stress on joints which tears them down. Excessive repetitive movements play a role because it eventually deteriorates the bones as they rub against each other. Age plays a role in arthritis, because throughout your life your joints will do a ton of rubbing together and eventually will start deteriorating. Inflammation as a reaction to disease plays a role in arthritis because it causes joints to be stiff, swollen, and…
Gout is a type of arthritis caused by a buildup of uric acid crystals in the joints. Uric acid is a breakdown product of purines that are part of many foods we eat.…
Rheumatoid Arthritis is a systemic disease, accompanied by progressive joint destruction and deformity. Depending on the severity, there may also be extra-articular manifestations, with involvement of the skin, blood vessels, eyes, lungs, heart, nerves, and internal organs. If inadequately treated, RA leads in the long term to a significant impairment of the quality of life; morbidity and mortality increase. The symmetric multiple joint involvement helps distinguish rheumatoid arthritis from other types of arthritis.…
The immune system helps to protect a person’s body from disease and infections. However if they have an autoimmune disease, the immune system attacks healthy cells in your body by mistake. R.A. can affect people of all ages ranging from kids to adults. According to the Arthritis Foundation about 1.5 million people in the United States have Rheumatoid Arthritis. It can affect three times as many women as it would in men. In women, R.A. usually begins between ages 30 and 60. In men, it often occurs later on in…
The name is based on the term "rheumatic fever", an illness which includes joint pain and is derived from the Greek word rheumatos ("flowing"). The suffix -oid ("resembling") gives the translation as joint inflammation that resembles rheumatic fever. The first recognized description of rheumatoid arthritis was made in 1800 by Dr Augustin Jacob Landré-Beauvais (1772-1840) of Paris.…