Facts/Research:
In the 1800’s people attempted to clone but weren’t successful. Hans Dreisch was the man in the 1800’s to try to clone a sea urchin. 1951 was the first successful clone which was a clone of a frog egg. The most common method of cloning is called “The Somatic Cell Nuclear Transfer” which requires two different cells. One cell is the Somatic …show more content…
One is a high failure rate, the success rate is .1-3 percent ( or 970-999 failures out of 1000). So reasons would be, the egg and the nucleus may not be compatible, an egg with a new nucleus may not divide or develop, the embryo inside the mother might fail, or the pregnancy itself might fail. Two is problems during later development… animals tend to be bigger in size when they are cloned and are to heavy to keep themselves up. “Large offspring syndrome” where their organs are abnormally large in size. Some clones that don’t have LOS have brain damage or impaired immune systems. Three, Abnormal gene expression patterns, scientists have to reprogram the nucleus in order for it to actually be a clone and sometimes the clone isn’t really a clone because a scientist didn’t reprogram the nucleus right. Four, Telomeric differences, if the nucleus is really old then the chromosomes telomeres (DNA sequence at both ends of the chromosomes) will be shorter. When the chromosomes, which are from a real animal, are short some of the clones have longer telomeres (they also have a longer life span, but dolly’s chromosomes had shorter telomeres and she aged faster than normal sheep). So scientists don’t really now why the chromosomes do that. Five, the clone can be born and then die a day