Economic:
Colonies moved westwards in order to settle more land, cutting trees down and clearing land for grazing animalsInitiated Anglo-Indian WarsSouthern colonies constantly engaging Indians on frontierPequot War (1634–1638) - armed conflict between the Pequot tribe and Massachusetts Bay and Plymouth coloniesMetacom’s War (King William’s War) (1675–1678)-armed conflict between Native American inhabitants of present-day New England and English colonistsMost colonists took advantage of Native Americans and established an unfair trade system
Cultural:
Received cultural accommodation from Squanto and the WampanoagMarriage between Pocahontas and John RolfeSpread diseases like smallpox, mumps, influenza, yellow fever,