Introduction define hcg cancer vaccine general use what will be disucsed in the essay
Subtitle one talk about trials explain trail and results advantages and disadvantages of hcg base vaccine
Subtitle two two other vaccines with adv disadv
Subtitle three ethical issues
Conclusions my opinion
References;
This essay will discuss the statement ‘current advances in hCG-based anti-cancer vaccine development’.
Human chorionic gonadotropin (hCG) is a placental glycoprotein hormone. This hormone is produced during pregnancy by the developing placenta after conception. It is later developed by the placental component syncytiotrophoblast. This hormone promotes the synthesis of progesterone. Progesterone is a steroid hormone; this hormone is part of the female menstrual cycle, also involved in pregnancy and embryogenesis. Cancerous tumours have been seen to produce this hormone; thus when there are elevated levels of this hormone and the patient is not pregnant, this would lead to a diagnosis of cancer. Nevertheless, it is unknown whether the elevated levels of hCG is a contributing cause of tumourigenesis or an effect of tumourigenesis.
The function of hCG is to maintain the corpus luteum, this is a temporary endocrine structure in females. This is associated with the production of rather high levels of progesterone, moderate levels of estradiol and inhibin A. If a female is not pregnant, the corpus luteum will degenerate within two weeks after its formation. This hormone also strongly stimulates steroid secretion by the corpus luteum in the beginning stages of gestation.
A vaccination is the stimulation of a person’s immune system by administrating antigenic material; this is done to create an adaptive immunity to a pathogen.
A cancer vaccination is a vaccination that treats existing cancer or prevents the development of cancer in particular higher risk patients. Treating existing cancer with
References: Molecular and Cellular Endocrinology (2007) states Moleuclar cellular endocrinology (2007)., ‘ Anti- hCG Trials’ available at: http://www.cancerbacteria.com/trial.html, accessed on 23.12.12 Clinical Cancer Research, (2004)., ‘A novel human cancer vaccine elicits cellular responses to the tumor-associated antigen, human chorionic gonadotropin beta’ available at: http://www.ncbi.nlm.nih.gov/m/pubmed/15041707/ accessed on 21.12.12.