Preview

Double Blind Randomized Controlled Trial

Good Essays
Open Document
Open Document
627 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Double Blind Randomized Controlled Trial
Double Blind Randomized Controlled Trial
The controlled and randomized double blind trials refer to a situation in which a medicine investigator is not familiar with the nature of a drug. The term may also mean that a scientist does not realize that a drug is being tested maybe for certain diseases. Such medicines may be under surveillance, and they are only administered in a small prescribed amount in case of any side-effects. For a typical scientific research, the desires, expectations and beliefs can subconsciously influence, often, how people perceive things. In clinical research and preliminary psychology, these values are broadly recognized, thus explaining the rationale on why studies from subjects are regularly carried out under both blind and double blind situations. There is irresistible empirical support, which reveals that the expectation and attitude of experimenters can actually have a great impact on the result of experiments (Schulz & Grimes, 2002).
In a situation involving single-blind experiments, an examiner is not able to distinguish between different samples of treatment. However, when human beings are concerned, such as in experimental psychology and medicine, double-blind events can be used to watch against the anticipation of both investigators and their subjects. For instance, in a double-blind clinical trial, tablets of drugs may be administered to patients. Neither patients nor researchers are conscious of such experiments, and the principal placebo effects typically take place during trials. At this stage, both physicians and patients consider a powerful new treatment is being tested. The static tablets are liable to work like the cure being considered, and can even provoke its distinctive consequences. Similarly, experimenter expectation effects are recognized in experimental psychology, and also turn up in researches on animal activities (Schulz & Grimes, 2002).
In a captivating historical description, Schulz and Grimes

You May Also Find These Documents Helpful

  • Better Essays

    Assignment 1

    • 1301 Words
    • 6 Pages

    If the sample to test is selected to favor the results of the drug company, it would be categorized as a confounding factor, but if instead the drug company is sponsoring a serious study where the sample is selected randomly and divided in treatment and control groups, the experiment will be fairly analyzed and the results will be closed to reality.…

    • 1301 Words
    • 6 Pages
    Better Essays
  • Good Essays

    ENTM 105

    • 681 Words
    • 5 Pages

    other scientists, the experiment cannot be assured that its driven conclusion is right or wrong.…

    • 681 Words
    • 5 Pages
    Good Essays
  • Satisfactory Essays

    Participants were also deceived about the aim of the experiment then again if they were well informed beforehand then the results would not have been natural. There was also low ecological validity, because the experiment took place in a lab therefore cannot be related to day to day life.…

    • 145 Words
    • 1 Page
    Satisfactory Essays
  • Powerful Essays

    Double-Blind Placebo-Controlled Study: An experimental study in which neither the researchers nor the subjects in the study are aware who is receiving the treatment or the placebo.…

    • 1835 Words
    • 8 Pages
    Powerful Essays
  • Good Essays

    This is because a human life is valued more than any other subject used in clinical trials. In order to ensure the efficacy and legitimacy of treatment, human subjects are the most accurate compared to animals. Human subjects cultivate concrete information and data necessary for the improvement of medicine and health care as a whole. Baillie, McGeehan, T.M. Garrett, and R.M. Garrett (2013) stated, “…human experimentation is necessary for medical progress. Animal testing is useful, but it cannot provide the final word on either safety or efficacy” (p. 300). On the contrary, this does not excuse the researcher from disregarding a clinical participant’s life and safety. According to Baillie et al. (2013), humans are not objects that are used however the researcher desires (p. 293). Human experimentation, conversely, has a long history of abuse. Many rules and guidelines have been set in place to prevent researchers from taking advantage of human subjects all in the name of “science”. Due to these unfortunate events, Institutional Review Boards (IRBs) have been established to protect and oversee the organization and conduction of human experimentation (Baillie et al., 2013). One historical event that led to the development of stringent biomedical experimentation rules and guidelines was the Tuskegee syphilis research experiment (Head, 2012). This experiment was widely acknowledged and is known as…

    • 1010 Words
    • 5 Pages
    Good Essays
  • Powerful Essays

    Clinical Trials: Journal of the Society for Clinical Trials is an international peer reviewed scholarly. The primary aim is the “dissemination and development of knowledge about the design, conduct, analysis, synthesis, history, ethics, regulation and clinical or policy impact of all types of clinical trials and related medical research methodologies.” (Sage Journals, 2013).…

    • 866 Words
    • 4 Pages
    Powerful Essays
  • Good Essays

    Ap psych unit 2 outline

    • 1223 Words
    • 5 Pages

    2.1 Single-blind- a research procedure where they don’t tell the participants that they are being given a test or treatment. It is used to prevent bias results.…

    • 1223 Words
    • 5 Pages
    Good Essays
  • Good Essays

    sample sizes usually indicate that a study cannot be generalized to a larger population. Samples…

    • 574 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Scientific experiments are performed as a way for humans to understand more about the world in which they live and themselves. However, the thirst for such knowledge has often resulted in ignoring the ethical implications of such experiments and thus has resulted in some of the worst human rights violations. In 1973 the Senate Subcommittee on Health held a series of hearings in an attempt to tackle the conundrum of risk versus reward in medicine and human experimentation. Much knowledge has been reaped from these experiments that have resulted in medicine being able to improve the quality and lifespan of many people’s lives. However, a lot of this knowledge has been gained through the sacrifices of others and sometimes these sacrifices were not made willingly. Thirty years later, Kazuo Ishiguro’s Never Let Me Go attempts to tackle the same conundrum by posing a question to readers that all experimenters…

    • 1683 Words
    • 7 Pages
    Good Essays
  • Good Essays

    Ethics- Monkey Drug Trial

    • 832 Words
    • 3 Pages

    The monkey drug trial study in 1969 turned out to violate a few ethical guidelines throughout the experiment tested. First comes debriefing, the monkey drug trial violated this guideline. Debriefing is to receive an explanation of a study or investigation after participation is complete. None of the monkey in the study was given an explanation of what was going to take place. The doctors did not give an explanation to the monkeys for the reason they were monkeys, they wouldn’t…

    • 832 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Psyc

    • 382 Words
    • 2 Pages

    Controlled experiments may result in artificial situations in which behavior is not normal and cannot be generalized to the real world.…

    • 382 Words
    • 2 Pages
    Good Essays
  • Powerful Essays

    1. To combat investigator influences the better use is a method called a double-blind procedure (eyewitness identification, 6-12 paragraphs, n.d.).…

    • 826 Words
    • 4 Pages
    Powerful Essays
  • Good Essays

    Discussion Questions

    • 567 Words
    • 3 Pages

    What essential characteristics distinguish a true experiment from other research designs? What ethical problems do you see in conducting experiments with humans?…

    • 567 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    Evidence Based Practice

    • 5324 Words
    • 22 Pages

    review of the available trials contributes to a synthesis of relevant knowledge (Jennings & Loan,…

    • 5324 Words
    • 22 Pages
    Powerful Essays
  • Good Essays

    Essay About Animal Testing

    • 1173 Words
    • 5 Pages

    The experimentation on animals may be an iniquitous act to some people; conversely, some people might see it as a tool used to save many lives. Animal experimentation in the medical field has been useful in many ways. Scientists are able to take information learned from animals and make educated guesses about the human body’s functions and determine a person’s reaction to a drug.…

    • 1173 Words
    • 5 Pages
    Good Essays