Drug Stdy

DRUG NAME | ACTION | INDICATION | CONTRAINDICATION | ADVERSE REACTION | NURSING RESPONSIBILITIES | GENERIC: Piperacilin + Tazobactam BRAND NAME: Piptazo DOSAGE: 4.5g FREQUENCY Q8 ROUTE: IV | CLASSIFICATION: Antibiotic; Piperacillin and enzyme inhibitor. Belongs to the class of penicillin combinations, including beta-lactamase inhibitors. Used in the systemic treatment of infections | intra – abdominal linfections w/ peritonitis | Hypersensitivity to penicillins, cephalosporins & β-lactam inhibitors | Hypersensitivity Reactions: Rash, pruritus and fever have been reportedGastrointestinal Effects: melena, gastritisHepatic Effects: Transient increases in aspartate aminotransferase (AST),alanine aminotransferase(ALT), alkaline phosphatase and bilirubin can occur.Renal Effects: Increases in serum concentrations of creatinine and blood urea nitrogen (BUN) may be observed.Effect on the Central Nervous System: Headache, MalaiseLocal Reactions: pain, inflammation, thrombophlebitis and edema | Piptaz should not be added to blood products or albumin hydrolysates and should not be mixed with other drugs in a syringe or infusion bottle due to possible problems with compatibility.Piptaz is not chemically stable in solutions that contain only sodium bicarbonate and solutions that significantly alter pH.Lactated Ringer's Solutionis not compatible with Piptaz.Piptaz is stable in glass and plastic containers (plastic syringes, IV bags and tubing) once used with compatible diluents | DRUG NAME | ACTION | INDICATION | CONTRAINDICATION | ADVERSE REACTION | NURSING RESPONSIBILITIES | GENERIC: Acetylcysteine BRAND NAME: Fluimucil DOSAGE: 1 sachet in 100 ml of water FREQUENCY TID ROUTE: oral | Exerts mucolytic action through its free sulfhydryl group which opensup the disulfide bonds in the mucoproteins thus lowering mucous viscosity. The exact mechanism of action in acetaminophen toxicity is unknown. It is thought to act