Disease Information, Diagnosis, and Treatment
Epstein-Barr Virus
Disease Information, Diagnosis, and Treatment
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For more Information www.cdc.gov/ncidod/diseases/ebv.htm www.emedicinehealth.com www.uptodate.com For more Information www.cdc.gov/ncidod/diseases/ebv.htm www.emedicinehealth.com www.uptodate.com Treatment * self-care at home for mononucleosis with rest, fluids, and over-the-counter pain medicines * avoid contact sports to prevent splenic rupture for one to two months * if necessary, steroids can be used to treat significant swelling in the throat or an enlarged spleen * for malignancies, chemotherapy, radiation, immunotherapy, bone marrow and stem cell transplants, and surgery
Treatment
* self-care at home for mononucleosis with rest, fluids, and over-the-counter pain medicines * avoid contact sports to prevent splenic rupture for one to two months * if necessary, steroids can be used to treat significant swelling in the throat or an enlarged spleen * for malignancies, chemotherapy, radiation, immunotherapy, bone marrow and stem cell transplants, and surgery 1) clinically diagnosed with symptoms and signs 2) lab tests indicating elevated white blood cell count, increased lymphocytes with greater than 10 percent atypical lymphocytes
3) positive heterophile antibody test
4) positive antibodies to the viral capsid antigen, the early antigen, and the EBV nuclear antigen (EBNA)
5) positive immunoglobulin M subclass (IgM) early in infection followed by increased immunoglobulin G subclass (IgG) occurs in two to four weeks after onset and persists for life