By Jonas Wilson, Ing. Med.
Punch biopsies require puncturing the skin to obtain tissue for microscopic and histo-pathological examination. A tube-shaped sharp cutting tool is rotated through the skin to the subcutaneous fat to obtain a cylindrically shaped specimen. This sample undergoes tissue fixation, preparation of slides and staining for microscopy or storage in solution for bacterial or viral culturing. Primary indications for punch biopsy are suspicious skin growths and inflammatory or bullous eruptions. Whereas, active infections and a known history of bleeding disorders are contraindications.
Results
Acquisition of results largely depends on the institution where the procedure was conducted. …show more content…
An abnormal result indicates possible infection, benign tumors (e.g. moles), precancerous lesions (e.g. actinic keratosis), cancerous growths (e.g. squamous cell carcinoma) and other skin conditions, such as eczema or psoriasis. Results that are suggestive of pathology often require further testing in order to treat and follow-up response to treatment and/or lesion progression. However, follow-up treatment may not be required in cases where the biopsy resulted in complete lesion removal and there is no chance of recurrence.
Complications
Puncturing may result in some degree of scaring. Healing is facilitated with using sutures, which and these greatly reduce healing time and the incidence of scaring. Furthermore, the skill and technique of the surgeon is important as these too play a major role in scar development. The neater the procedure, the less the risk of developing a significant scar.
The procedure typically requires the use of local anesthetic; thus, a patient will not need to stay in a hospital following the procedure and may resume daily activities directly after. Allergy to local anesthetic or deep sedation, however, may cause complications. Evidence of allergic reaction includes vesicles, itch and erythema. Peripheral vasodilation is usually self-limited, but may result in fainting, sweating and