This vulnerability affects many types of the population who indulged in the clinical trial such as illiterates, mentally challenged people, poor people and the children. During undue inducements, the subjects are offered with the proposal for which they are unable to refuse. It is highly controlling, influencing irresistible and strong enough to compel the subject to participate in the research against their interest. Moreover, the poor people are more attracted towards the reimbursement and compensation provided to them. That results in a skewed sample and considered disadvantageous for socio-economical welfare by giving disproportionate burden. Coercion is also considered as an ethical issue, although it is rare. It gives threat to the subject to participate in the study, maybe by compromising the care in the treatment by refusing for their participation or by the physician as of the reality that the care provided is contingent to the participant or it is often misunderstood as meaning with the involuntary or under the strong influence. As coercion is not the harmful accusation, the better clarification is required and should be used carefully. Apart from that, a commodification of the subjects during the trials is also considered as a severe ethical issue, as the participant does not deserve that because they are risking their health by engaging into study whose outcomes are still
This vulnerability affects many types of the population who indulged in the clinical trial such as illiterates, mentally challenged people, poor people and the children. During undue inducements, the subjects are offered with the proposal for which they are unable to refuse. It is highly controlling, influencing irresistible and strong enough to compel the subject to participate in the research against their interest. Moreover, the poor people are more attracted towards the reimbursement and compensation provided to them. That results in a skewed sample and considered disadvantageous for socio-economical welfare by giving disproportionate burden. Coercion is also considered as an ethical issue, although it is rare. It gives threat to the subject to participate in the study, maybe by compromising the care in the treatment by refusing for their participation or by the physician as of the reality that the care provided is contingent to the participant or it is often misunderstood as meaning with the involuntary or under the strong influence. As coercion is not the harmful accusation, the better clarification is required and should be used carefully. Apart from that, a commodification of the subjects during the trials is also considered as a severe ethical issue, as the participant does not deserve that because they are risking their health by engaging into study whose outcomes are still