Through the first ten years of operation outbreaks of hepatitis were common at the institution.This led to a controversial medical study carried out between 1963 and 1966 by medical researchers Saul Krugman and Robert W. McCollum. Healthy children were intentionally inoculated, orally and by injection, with the virus that causes the disease, and then monitored to gauge the effects of gamma globulin in combating it. (New York Times, 2010). Some of the early subjects were said to have been fed extracts of stools from infected individuals and later subjects received injections of more purified virus preparations.
The actual study involved more than 700 children at Willowbrook. The experimental group included children already at Willowbrook who were injected with protective antibodies. The control group did not receive the injection. Krugman then observed the degrees of immunity to hepatitis in both groups. In a second study, researchers injected newly admitted children with protective antibodies. Some of these students were deliberately infected with a Willowbrook
References: A Guide to Willowbrook State School Resources at Other Institutions Retrieved February 2, 2011 Boylin, J, & Scott, J. (2006). Practicum internship: textbook and resource guide for counseling and psychotherapy [Fourth Edition]. (Google E-book), Retrieved from http://www.google.com/search?hl=en&q=Fusillo,+Maureen+C.+The+Willowbrook+State+School:+An+Oral+History.+Student+Project.+%5BS.I.+s.n.,+1994%5D.&tbo=u&tbs=bks:1&source=og&sa=N&tab=sp#sclient=psy&hl=en&tbs=bks:1&q=APA+Ethical+Principles+of+Psychologists+and+Code+of+Conduct&aq=0p&aqi=p-p2g2g-o1&aql=f&oq=&pbx=1&fp=1&cad=b Hevesi, Dennis. "Robert W. McCollum, Dean of Dartmouth Medical School, Dies at 85",The New York Times, September 25, 2010. Accessed February 3, 2011 Marsden, S, & Malander, M. (2001). Historical cases of unethical research. Unpublished manuscript, University of North Dakota, North Dakota. Retrieved from http://www.und.edu/instruct/wstevens/PROPOSALCLASS/MARSDEN&MELANDER2.htm Milestones in OMRDD 's History, OMRDD, (2001-09-19). Retrieved on 2011-02-03- Powers, Ron (1977), The Newscasters: The News Business as Show Business, New York: St. Martin 's Press, p. 185, ISBN 0-312-5707-7 Rivera, Geraldo. Willowbrook: A Report on How It Is and Why It Doesn’t Have to Be That Way. New York: Random House, 1972. ISBN 0394718445 Staff. "Excerpts From Statement by Kennedy", The New York Times, September 10, 1965. Accessed September 26, 2010. The Praeger Handbook of Special Education - by Alberto M. Bursztyn - Praeger Publishers; 1 edition (December 30, 2006) ISBN 0313332622