European Consumer Exposure to Cosmetic Products
Food and Chemical Toxicology 45 (2007) 2097–2108 www.elsevier.com/locate/foodchemtox
Review
European consumer exposure to cosmetic products, a framework for conducting population exposure assessments
B. Hall a,*, S. Tozer b, B. Safford c, M. Coroama d, W. Steiling e, M.C. Leneveu-Duchemin f, C. McNamara g, M. Gibney h b a ` ´ L’Oreal, Worldwide Safety Evaluation, River Plaza 25-29 quai Aulagnier, 92600 Asnieres-sur-Seine, France Procter & Gamble, Central Product Safety, P&G Technical Centres Ltd., Whitehall Lane, Egham, Surrey TW20 9NW, UK c Unilever, Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Beds MK44 1LQ, UK d Colipa, Avenue Hermann-Debroux 15A, B-1160 Brussels, Belgium e Henkel KGaA, Corporate SHE and Product Safety-Human Safety Assessment, Henkelstr. 67, 40191 Dusseldorf, Germany f Beiersdorf AG, Unnastrasse 48, 20245 Hamburg, Germany g CREMe Software Ltd., Innovation Centre, Trinity College, Dublin 2, Ireland h Agriculture and Food Centre, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
Received 31 January 2007; accepted 1 June 2007
Abstract Access to reliable exposure data is essential to evaluate the toxicological safety of ingredients in cosmetic products. This study was carried out by European cosmetic manufacturers acting within the trade association Colipa, with the aim to construct a probabilistic European population model of exposure. The study updates, in distribution form, the current exposure data on daily quantities of six cosmetic products. Data were collected using a combination of market information databases and a controlled product use study. In total 44,100 households and 18,057 individual consumers in five European countries provided data using their own products. All product use occasions were recorded, including those outside of home. The raw data were analysed using Monte Carlo simulation and a European Statistical Population Model of exposure was
Review
European consumer exposure to cosmetic products, a framework for conducting population exposure assessments
B. Hall a,*, S. Tozer b, B. Safford c, M. Coroama d, W. Steiling e, M.C. Leneveu-Duchemin f, C. McNamara g, M. Gibney h b a ` ´ L’Oreal, Worldwide Safety Evaluation, River Plaza 25-29 quai Aulagnier, 92600 Asnieres-sur-Seine, France Procter & Gamble, Central Product Safety, P&G Technical Centres Ltd., Whitehall Lane, Egham, Surrey TW20 9NW, UK c Unilever, Safety and Environmental Assurance Centre, Colworth Park, Sharnbrook, Beds MK44 1LQ, UK d Colipa, Avenue Hermann-Debroux 15A, B-1160 Brussels, Belgium e Henkel KGaA, Corporate SHE and Product Safety-Human Safety Assessment, Henkelstr. 67, 40191 Dusseldorf, Germany f Beiersdorf AG, Unnastrasse 48, 20245 Hamburg, Germany g CREMe Software Ltd., Innovation Centre, Trinity College, Dublin 2, Ireland h Agriculture and Food Centre, Food Science and Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
Received 31 January 2007; accepted 1 June 2007
Abstract Access to reliable exposure data is essential to evaluate the toxicological safety of ingredients in cosmetic products. This study was carried out by European cosmetic manufacturers acting within the trade association Colipa, with the aim to construct a probabilistic European population model of exposure. The study updates, in distribution form, the current exposure data on daily quantities of six cosmetic products. Data were collected using a combination of market information databases and a controlled product use study. In total 44,100 households and 18,057 individual consumers in five European countries provided data using their own products. All product use occasions were recorded, including those outside of home. The raw data were analysed using Monte Carlo simulation and a European Statistical Population Model of exposure was
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