Preview

Faulty Cfr Gene Formation

Satisfactory Essays
Open Document
Open Document
88 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Faulty Cfr Gene Formation
How is it inherited?
Each individual acquires two CFTR gene, one from each parent. Kids who inherit a faulty CFTR gene from each parent will inherit cystic fibrosis. Youngsters who obtain one faulty CFTR gene and one ordinary CFTR gene are known as “CF carriers”. CF carriers has no indications of CF and live typical lives. Although, they can pass the faulty CFTR gene to their youngsters.
The picture beneath demonstrates how two parents who are both CF carriers can pass the faulty CFTR gene to their kids.

You May Also Find These Documents Helpful

  • Better Essays

    Unit Project 4

    • 1226 Words
    • 5 Pages

    Male reproductive tract – males with CF are sterile due to degeneration and/or obstruction of the vas deferens.…

    • 1226 Words
    • 5 Pages
    Better Essays
  • Powerful Essays

    Cystic fibrosis is an autosomal (not sex linked), hereditary disease caused by a mutation in the gene called the cystic fibrosis transmembrane conductance regulator gene, or the CFTR gene. This CFTR gene belongs to a group of genes called ABC (ATP-binding cassette). These are transport molecules for molecules such as phosphate, glucose, chloride, and peptides. Specifically for the CFTR gene, the molecules transported are chloride and sodium. The CFTR protein, which is created by the CFTR gene, has a molecular weight of 168,173 daltons and in length, is 1480 amino acids long. This variation in genes is located in chromosome 7 of humans. Because most people have two of the CFTR gene which creates the CFTR proteins, a person can be completely healthy with a mutation in the gene, as long as at least one of these genes are unchanged from the normal state. Without the cystic fibrosis variation of the CFTR gene, the CFTR proteins created by the gene act as a channel protein which can be found in the membranes of cells which line the passageways of organs such as the pancreas, lungs, and intestines. The CFTR protein can be modified in numerous ways to give the host cystic fibrosis; in fact, over 1000 transformations of the CFTR gene have been recognized. One of the most common of these mutations is a deletion of a single amino acid from the long chain of 1480 in the CFTR protein. This causes a breakdown of the channel made with the missing amino acid, which means that it never transports chloride ions, like it was made to do, because it never reaches the cell membrane. This mutation is delta F508, because the deletion occurs at position 508 on the CFTR protein. These sorts of mutations work to deteriorate and destroy the efficiency of the CFTR protein by changing or replacing parts of the protein’s amino acid order. This order chooses the way that the protein is folded, and if this order is…

    • 1736 Words
    • 7 Pages
    Powerful Essays
  • Good Essays

    Cystic Fibrosis is an inherited condition. However, the gene for Cystic Fibrosis is recessive and one strand must be inherited from each parent. Therefore, not all children of people with this condition develop it. But of course they are at increased risks of developing the condition. Both parents must either have Cystic Fibrosis, or be a carrier. Since it is a recessive gene, if a child has parents with Cystic Fibrosis and does not develop the condition, he or she will still have the recessive gene and become a carrier. Therefore, their children will now be at risk (Moe, 1992, p. 70).…

    • 802 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    Cystic fibrosis is a genetic disease, and it is inherited by autosomal recessive, which means that there must be two copies of an abnormal gene and it has to be present in order for the disease or trait to develop. While I was learning about autosomal recessive, I learned that gene’s come in pairs and both pairs must be defective to cause a disease. As I looked deeper into Cystic fibrosis I learned that it affects the respiratory system and also the digestive system. This disease is a defect in the chromosome 7, chromosome 7 is also known as CFTR or cystic fibrosis transmembrane conductance regulator. Like most diseases these days the way it affects someone or shows in someone depends on the severity of the disease. For instance, the way cystic fibrosis shows in a child may be completely different compared to someone in there later ages. For the most part the symptoms are always the same for both the respiratory and the digestive system. When it comes to the respiratory system the symptoms that you need to look for is a constant cough that produces a lot of mucus, Wheezing or feeling breathlessness. Always having a stuffy nose and not being able to exercise the way you may want too is also a symptoms due to the respiratory system. As you can tell from the…

    • 960 Words
    • 3 Pages
    Satisfactory Essays
  • Powerful Essays

    Unit 4 P3 Research Paper

    • 2638 Words
    • 11 Pages

    Is an illness which is genetically passed on, it is caused by a defective gene. The cystic fibrosis gene is recessive, this means that if a child has a parent who carries the gene they will not get the illness unless the other parent also carries the gene however, there is a 1 in 4 chance of catching the disease. Cystic fibrosis causes excess production of a defective protein that causes the lungs to become full of sticky thick mucus. Sufferers of Cystic fibrosis can have…

    • 2638 Words
    • 11 Pages
    Powerful Essays
  • Satisfactory Essays

    Tay-Sachs Disease

    • 571 Words
    • 3 Pages

    A person can be a carrier of the faulty gene (a genetic carrier for TSD) if they have inherited a working HexA gene copy from one parent and a faulty HexA gene copy from the other parent. However, carriers with just one faulty HexA gene copy will never develop…

    • 571 Words
    • 3 Pages
    Satisfactory Essays
  • Better Essays

    will occur if the mutation is on the maternally inheritetd chromosome 15. [See picture to the left] This accounts…

    • 924 Words
    • 4 Pages
    Better Essays
  • Good Essays

    For a baby to be born with Cystic Fibrosis, both parents must be carriers of the faulty CF gene. The diagram shows how CF is inherited. Where both parents carry the faulty gene, each child has a one in four chance of having CF, a two in four chance of being a carrier and a one in four chance of not having any CF genes.…

    • 505 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Cystic Fibrosis is caused by a fault in the cystic fibrosis transmembrane conductance regulator (CFTR) gene on chromosome 7 at q31.2. For CF to be expressed, a faulty copy of the gene must be present at both alleles; autosomal recessive. Therefore both parents must be carriers of, or affected by the cystic fibrosis gene (fig. 1) for the gene to be passed on. If a person has one copy of the faulty allele (are heterozygous) they are carriers of the gene and can pass this allele on; if they possess two copies of the faulty allele (are homozygous), they will have CF. People who have CF must consider that their children will definitely be carriers at the very least, and depending on the genotype of their partner, may also suffer from CF.…

    • 883 Words
    • 4 Pages
    Good Essays
  • Powerful Essays

    Cystic Fibrosis

    • 1756 Words
    • 8 Pages

    Cystic fibrosis (CF) is a worldwide autosomal recessive disorder genetically inherited that causes chronic progressive health alterations of the bodily systems (Lyczak et al, 2004, p. 194). Mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR), located on the long arm of chromosome seven, results in many abnormal traits with organ function, specifically the respiratory, reproductive, and digestive systems that are genetically passed down from parents to their children (Lomas & Fowler, 2010, p. 30). A mutation causes the CFTR gene to be defective, thus producing an altered structure of chloride and sodium channel proteins found in the cells of the exocrine glands responsible for producing mucus, sweat, and digestive juices, which are vital for the normal functioning of the respiratory and digestive systems (Lomas & Fowler, 2010, p. 31).…

    • 1756 Words
    • 8 Pages
    Powerful Essays
  • Satisfactory Essays

    Cystic fibrosis is a recessive trait. If you have one CF gene and one non-CF gene, you will be a carrier but not have CF. I referred back to Mendel mentioning that the trait may not show up in somebody but it can still be passed on to the next generation. He also states that the inheritance of each trait is determined by genes that are passed on unchanged. So as the CF gene is not present, it becomes present depending on the ratio of genes as it passes down.…

    • 418 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    Cystic fibrosis (CF) is a lifelong hereditary/genetic disorder, meaning the disease can be passed on from parent to child and can be inherited. CF is not contagious. Both parents must be either a carrier or suffer from CF for the disease to be passed on however carriers show no symptoms that a suffer does. CF affects the respiratory system; mainly the lungs and some parts of the digestive and reproductive systems including the pancreas, liver and the vas deferens in males. This is due to a malfunction of the exocrine system (system responsible for the excretion of sweat, saliva, tears, and mucus).…

    • 631 Words
    • 3 Pages
    Good Essays
  • Good Essays

    Children who inherit a faulty CFTR gene from each parent will have CF. Children who inherit one faulty CFTR gene and one normal CFTR gene are ‘CF carriers’. CF carriers usually have no symptoms of CF and live normal lives, however they can pass the faulty CFTR gene to their children.…

    • 933 Words
    • 4 Pages
    Good Essays
  • Good Essays

    Cystic Fibrosis

    • 569 Words
    • 3 Pages

    What is cystic fibrosis? Cystic fibrosis is a disease that is passed down through families, from parent to child due to a faulty gene. It currently affects both babies, children and young adults. This faulty gene controls the movement of salt and water in and out of the cells, so the lungs and digestive system become so clogged with mucus, it makes it hard to breathe and digest food.…

    • 569 Words
    • 3 Pages
    Good Essays
  • Good Essays

    What Is Cystic Fibrosis?

    • 1758 Words
    • 8 Pages

    According to the World Health Organization, the occurrence of cystic fibrosis varies across the world. In the United States, approximately 1 in 3,500 babies are born with cystic fibrosis while in the European Union there are approximately 1 in 2,000 to 3,000 babies born with cystic fibrosis. In the United States, approximately 800-900…

    • 1758 Words
    • 8 Pages
    Good Essays