The 4 major types of cells that are found in the human body are keratinocytes, melanocytes, epidermal dendritic (Langerhans), and the tactile (Merkel) cells. The keratinocytes, which are epithelia cells, are the most abundant cells in human body and dominate the epidermis. These cells contain keratin and work together to form layers known as thick skin, which consists of 5 layers, and thin skin, which consists of 4 layers. These cells are in the stratum granulosm and stratum spinosum layers. The melanocytes which are in the stratum basale, are known to synthesis melanin. These cells are responsible for the pigmentation of our skin. The melanin that is synthesized by the melanocytes …show more content…
When referring to the epidermis and the thickness of the area of the skin we are refering to, there are four or five layers that composed together. The layers are the stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, and the stratum corneum. The stratum basale is the deepest layer and is attached to the basement membrane and has one layer of active mitotic stem cells. This layer forms epidermal ridges which push up through the rest of the layers to form your unique fingerprints. In the stratum spinosum layer, keratinocytes are bound together by desmosomes. This layer also contains dendritic cells that take part in the immune response. The stratum granulosum consists of displaced cells from the stratum spinosum. Here the keratinocytes produce large amounts of water proof protein known as keratin. The cells have stopped dividing in this layer. The stratum lucidum layer is only found in parts of the body that have thick skin like the palms of the hands and soles of the feet and almost appears to be glassy. The cells in this layer are flattened, densely packed, and filled with keratin. The last layer in the epidermis is known as the stratum corneum. This layer consists of 20 to 30 layers of dead, interlocking, and flattened keratinocytes. It’s considered to be water resistant but not water