The novel, or diary, deals with the downfall of a young teenage girl in America, and her journals over the course of two years and a few days. At the beginning of the book, "Alice" is a typical, insecure, middle-class teenager preoccupied with boys, diets, and popularity. Her fortunes take a sharp turn for the worse when her family moves to a new town and she finds herself less popular and more isolated than ever before. Unhappy in the new town, she is overjoyed to be allowed to return to the old town to spend the summer with her grandparents. During this stay she is invited to a party by an old acquaintance; there she unwittingly ingests LSD that had been added to random bottles of Coca-Cola and distributed to the party guests as a game. The other guests had mistakenly assumed Alice was aware of what the "game" entailed. After this first unwitting, but pleasurable, experience, she seeks drugs deliberately, and rapidly proceeds to marijuana,and amphetamines. She describes her drug experiences intricately; the more extreme the supposed diarist's drug experience, the more sophisticated and descriptive her writing becomes.
A pregnancy scare and the return to her new town encourage her to turn away from drugs; however she soon willingly falls in with the drug crowd where finally she finds acceptance. She starts dating a drug dealer and sells drugs to grade-schoolers for him. After realizing he was using her, she turns him in to the police and runs away from home with her new friend Chris, moving to San Francisco. She opens a boutique with Chris, however she misses her family. After being given heroin and then being raped by Chris' boss, Shelia, and her boyfriend, she and Chris return home.
She is welcomed back warmly by her family, but finds herself ostracized by the community and has difficulty keeping her resolve to avoid drugs. She soon weakens and, while high, runs away again. She spends time living on the streets, a period during which her