Grignard Synthesis Lab Report
The Grignard Synthesis of Triphenylmethanol
Abstract: Grignard synthesis of triphenylmethanol was achieved by use of the Grignard reagent phenyl magesium brominde. The organometallic grignard reagent was synthesized by use of a reflux apparatus recrystallization techniques. Once synthesized it was used in a Grignard reaction that involved nucleophilic addition to a carbonyl in order to make triphenylmethanol. The final product was solidified and recrystallized and spectral data was obtained to confirm its presence.
Introduction:
Carbon-carbon bonds are the basis of organic chemistry. Attaching carbons and other organic molecules together we can create new molecules and carry out even more reactions to further manipulate …show more content…
These substantial differences in electronegativity induce a separation of charge where the electrons are not evenly distributes over the entire molecule. As a result, these compounds can be difficult to control. Examples include NaCH3 and KCH2CH2CH3. The metals in both of these compounds have an oxidation of +1, which puts leaves a positive charge on the metal and a negative charge on the organic group. This makes the molecule even more unstable because typically these organic groups do not like a negative …show more content…
Specifically the bond dissociation energy of a molecule reflects teh stability of the initial and final states. A lower BDE ensures stability and lowers the likelihood of hemolytic cleavage and eventual formation of a Grignard. Benzyllic radical R groups are the most stable due to electron delocalization in their resonance structure. Allylic radical R groups are also stable as their double bonds allow for similar resonance stabilization. Tertiary, Secondary, and Primary radicals follow in stability. They are followed by methyl radicals and finally phenyl
Abstract: Grignard synthesis of triphenylmethanol was achieved by use of the Grignard reagent phenyl magesium brominde. The organometallic grignard reagent was synthesized by use of a reflux apparatus recrystallization techniques. Once synthesized it was used in a Grignard reaction that involved nucleophilic addition to a carbonyl in order to make triphenylmethanol. The final product was solidified and recrystallized and spectral data was obtained to confirm its presence.
Introduction:
Carbon-carbon bonds are the basis of organic chemistry. Attaching carbons and other organic molecules together we can create new molecules and carry out even more reactions to further manipulate …show more content…
These substantial differences in electronegativity induce a separation of charge where the electrons are not evenly distributes over the entire molecule. As a result, these compounds can be difficult to control. Examples include NaCH3 and KCH2CH2CH3. The metals in both of these compounds have an oxidation of +1, which puts leaves a positive charge on the metal and a negative charge on the organic group. This makes the molecule even more unstable because typically these organic groups do not like a negative …show more content…
Specifically the bond dissociation energy of a molecule reflects teh stability of the initial and final states. A lower BDE ensures stability and lowers the likelihood of hemolytic cleavage and eventual formation of a Grignard. Benzyllic radical R groups are the most stable due to electron delocalization in their resonance structure. Allylic radical R groups are also stable as their double bonds allow for similar resonance stabilization. Tertiary, Secondary, and Primary radicals follow in stability. They are followed by methyl radicals and finally phenyl