As Hernán Cortés came in contact with the natives, he was able to unknowingly transfer smallpox along with other various diseases to natives. Therefore, after their first battle with the Spaniards, the Aztecs were overwhelmed with illness. This led to the fall of great Aztec Empire.
However, even before this the Inca Empire had been swept by with the illness, smallpox, too.
In order to rid themselves of the—curse (smallpox)—the gods had placed on them, the natives introduced new the religious ritual of drum and rattle incantations.
However, due to the decline in the population, the Aztecs were quick to lose the war against the Spanish conquistadors.
During the Exploration
• The Aztecs