CANCER, a 6 letter word that makes our world upside down.
Cancer is not just one disease, but a large group of almost 100 diseases. Its two main characteristics are uncontrolled growth of the cells in the human body and the ability of these cells to migrate from the original site and spread to distant sites. If the spread is not controlled, cancer can result in death. 2.How does cancer occur? The body is made up of trillions of living cells. These cells grow, divide, and die in an orderly fashion. This process is a tightly regulated one that is controlled by the DNA machinery within the cell. When a person is a baby or a child or within his or her mother’s womb, cells divide rapidly to allow for growth. After the person becomes an adult, most cells divide only to replace worn-out or dying cells or to repair injuries. When cells of the body at a particular site start to grow out of control, they may become cancerous. Cancer cell growth is different from normal cell growth. Instead of dying, cancer cells continue to grow and form new, abnormal cells. In addition, these cells can also invade other tissues. This is a property that normal cells do not possess. 3.Molecular pathology behind cancer Cancer cells originate from normal cells when their DNA (deoxyribonucleic acid) or blue prints within the cell nucleus is damaged. DNA is in every cell and it directs all the cell’s actions, growth, death, protein synthesis etc. When DNA is damaged in a normal cell, the cell either repairs the damage or the cell dies. In cancer cells, the damaged DNA is not repaired, and the cell does not die. Instead it gives rise to more such abnormal cells with abnormal DNA. These new cells all have the same defective DNA of the original cancer cell. DNA damage may be inherited from parents or may be a spontaneous problem that occurs during the lifetime of a person. DNA damage may also be triggered by exposure to certain environmental toxins such as those present in