Keeping Up with the Jones
Keeping Up With the Jones’s Case Study
Directions: Complete Parts 1-6 of this case study. http://www.sciencecases.org/jones/jones.asp Submit Answers to the Following Questions:
Part I: 1. What two parameters are responsible for creating the movement (filtration and reabsorption) of fluid across the capillary wall? The hydrostatic pressure (or blood pressure) and osmotic pressure (water pressure) are responsible for balancing and creating the movement of fluid across the capillary wall. 2. Find a diagram of a capillary – copy/paste and cite the source. [pic] http://cikgurozaini.blogspot.com/2011/01/fluid-exchange.html 3. Under normal circumstances, what components of the blood cross the capillary wall? Interstitial fluid travels across capillary walls. Water and other small solutes can also diffuse across the wall but blood cells cannot. 4. Cytokines, like histamine and leukotrienes, are secreted by damaged cells in Dave’s ankle. How do these cytokines cause inflammation? Cytokines from injured cells induce the expression of E-selectin on endothelial cells, which functions similarly to P-selectin. 5. How does the application of ice to the ankle affect blood flow through the capillaries? The application of ice causes constriction of the capillaries. This decreases the blood flow to the ankle and reduces swelling. 6. How does the removal of ice from the ankle affect blood flow through the capillaries and the cytokines? This will return the blood flow and cytokines to normal. The blood flow will increase. 7. How does compression, which is provided by an elastic (Ace) bandage wrapped around the damaged ankle, decrease inflammation? The ace bandage will physically constrict the blood vessels of the ankle. This will in turn reduce inflammation and pain. 8. How does elevation of the damaged ankle decrease inflammation? This will increase blood flow back to the heart and
Directions: Complete Parts 1-6 of this case study. http://www.sciencecases.org/jones/jones.asp Submit Answers to the Following Questions:
Part I: 1. What two parameters are responsible for creating the movement (filtration and reabsorption) of fluid across the capillary wall? The hydrostatic pressure (or blood pressure) and osmotic pressure (water pressure) are responsible for balancing and creating the movement of fluid across the capillary wall. 2. Find a diagram of a capillary – copy/paste and cite the source. [pic] http://cikgurozaini.blogspot.com/2011/01/fluid-exchange.html 3. Under normal circumstances, what components of the blood cross the capillary wall? Interstitial fluid travels across capillary walls. Water and other small solutes can also diffuse across the wall but blood cells cannot. 4. Cytokines, like histamine and leukotrienes, are secreted by damaged cells in Dave’s ankle. How do these cytokines cause inflammation? Cytokines from injured cells induce the expression of E-selectin on endothelial cells, which functions similarly to P-selectin. 5. How does the application of ice to the ankle affect blood flow through the capillaries? The application of ice causes constriction of the capillaries. This decreases the blood flow to the ankle and reduces swelling. 6. How does the removal of ice from the ankle affect blood flow through the capillaries and the cytokines? This will return the blood flow and cytokines to normal. The blood flow will increase. 7. How does compression, which is provided by an elastic (Ace) bandage wrapped around the damaged ankle, decrease inflammation? The ace bandage will physically constrict the blood vessels of the ankle. This will in turn reduce inflammation and pain. 8. How does elevation of the damaged ankle decrease inflammation? This will increase blood flow back to the heart and