Prevalence: Keratoconus is estimated to occur in 1 out of every 2000 persons in the general population. There appears to be no significant preponderance with regards to either men or women.
What is the usual age of onset of keratoconus?
The onset of keratoconus is between the ages of 10 and 30. The changes in the shape of the cornea usually occur slowly over several years.
Symptoms: Symptoms depend on the severity of the disease. The most common symptoms include:
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In early stage, impaired vision in one eye caused by progressive Irregular myopic astigmatism with steep keratometry reading.
2. Scissor reflex on retinoscopy.
3. Ophthalmoscopically shows an "Oil droplet reflex".
4. Munson sign-Bulging of lower lid in down gaze.
5. Fleischer Ring-Epithelial iron deposits at the base of the cornea. Mechanism of iron deposition is not clear understood. It may be uneven distribution of tears.
6. Progressive Central or paracentral stromal thinning with inferior apical protrusion.
7. Vogt striae-Fine deep vertical stromal folds which temporarily disappear on digital pressure.
8. Rizutti sign-conical reflection on the nasal cornea when light is shone from the temporal side.
9. Prominent corneal nerves.
10. Acute Hydropes-Corneal edema resulting from tears Due to ruptures of the descemet`s membrane and acute seepage of the aqueous humor into the corneal stroma and epithelium. These breaks usually heal within 6-10 weeks and the edema gradually clears.
11. Variable corneal scarring, depending on severity of the disease.
Associations: The ocular and systemic associations of the keratoconus include:
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