Laforin Isoform Research Paper

Laforin Isoform creates the protein tyrosine phosphatase. It is important to maintain an appropriate amount of tyrosine because it is essential for many cellular functions The disease is caused by mutations of the EMP2A gene, .As a consequence, maintaining an appropriate level of protein tyrosine phosphorylation is essential for many cellular functions. Tyrosine-specific protein phosphatases stimulate the removal of a phosphate group attached to a tyrosine residue, using a cysteinyl-phosphate enzyme intermediate. (2009)
One of the two isoforms created by the EPM2A gene is located in the cytoplasm of a cell, the other is in the nucleus.. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the