Loradatine Research Paper
Loradatine
a. The names given are the Generic name, you need to find the Brand name and the company that produces it.
Loradatine : Claritin, Schering-Plough
b. What is the mechanism of action.
Like other H1-blockers, loratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Claritin also has a weak affinity for acetylcholine and alpha-adrenergic receptors.
c. What is the use of the medication. The specific conditions that are treated with it.
Claritin is an antihistamine that relieves the sneezing, runny nose, stuffiness, itching, and tearing eyes caused by hay fever or other upper respiratory allergies. It also relieves the swollen, red, itchy patches of skin caused by …show more content…
hives. Claritin is also available as an over-the-counter product.
d. Side Effect of the prescription drug.
Common side effects include: dizzines drowsiness dry mouth
This medicine can cause excitement especially in children.
See a doctor immediately if you experience: fast or irregular heartbeat mental or mood changes tightness in the chest unusual tiredness or weakness.
e. Any important fact that calls your attention. If you have liver or kidney disease, your doctor should prescribe a lower starting dose of Claritin.
f. Dosage and how should it be taken.
10 mg tablets per day, to be administered orally
g. When should not be prescribed.
Do not take Claritin if you are sensitive to or have ever had an allergic reaction to it. Make sure your doctor is aware of any drug reactions that you have experienced.
h. Possible food and prescription drug Interaction. Although no harmful interactions with Claritin have been reported, there is a theoretical possibility of an interaction with the following drugs: Antibiotics such as erythromycin Cimetidine (Tagamet) Ketoconazole (Nizoral) Do NOT take this medicine with orange, apple or grapefruit juice. The levels of this medicine in your blood may be decreased by 70%.
Diphenydramine
a. The names given are the Generic name, you need to find the Brand name and the company that produces it. diphenydramine: Benadryl, Pfizer
b. What is the mechanism of action Blocks cellular histamine receptors; decreases vasodilation; decreases motion sickness. Reverses extrapyramidal reactions.
c. What is the use of the medication. The specific conditions that are treated with it. Benadryl is an antihistamine with drying and sedative effects. It relieves red, inflamed eyes caused by food allergies and the itching, swelling, and redness from hives and other rashes that are caused by mild allergic reactions. It also relieves the sneezing, coughing, runny or stuffy nose, and red, teary, itching eyes caused by seasonal allergies (hay fever) and the common cold. Benadryl is also used to treat allergic reactions to blood transfusions, to prevent and treat motion sickness, and, with other drugs, to treat anaphylactic shock (severe allergic reaction) and Parkinson's disease, a nerve disorder characterized by tremors, stooped posture, shuffling walk, muscle weakness, drooling, and emotional instability.
d. Side Effect of the prescription drug. • common side effects may include: Disturbed coordination, dizziness, excessive calm, increased chest congestion, sleepiness, stomach upset • Less common or rare side effects may include: Anaphylactic shock (extreme allergic reaction), anemia, blurred vision, chills, confusion, constipation, convulsions, diarrhea, difficulty sleeping, double vision, dry mouth, nose, throat, early menstruation, excessive perspiration, excitation, fast, fluttery heartbeat, fatigue, frequent or difficult urination, headache, hives, inability to urinate, increased sensitivity to light, irregular heartbeat, irritability, loss of appetite, low blood pressure, nausea, nervousness, rapid heartbeat, rash, restlessness, ringing in the ears, stuffy nose, tightness of chest and wheezing, tingling or pins and needles, tremor, unreal or exaggerated sense of well-being, vertigo, vomiting
e. Any important fact that calls your attention Antihistamines may produce excitability in children. In the elderly they may cause dizziness, excessive calm, or low blood pressure.
f. Dosage and how should it be taken. Benadryl reaches its peak effect in 1 hour, and 1 dose will continue to work for 4 to 6 hours.
ADULTS
The usual recommended dose is 25 to 50 milligrams 3 or 4 times daily. The sleep-aid dosage is 50 milligrams at bedtime.
Motion Sickness
For prevention of motion sickness, take the first dose 30 minutes before exposure to motion; take the other doses before meals and at bedtime for as long as the motion continues.
CHILDREN (OVER 20 POUNDS)
The usual dose is 12.5 to 25 milligrams, 3 to 4 times daily. A child should not take more than 300 milligrams a day.
This medication should not be used as a sleep aid for children under age 12.
Your physician will determine the best use of the drug in response to its effects on the child.
g. When should not be prescribed. Benadryl should not be used in newborn or premature infants, or if you are breastfeeding your infant. Do not take this medication if you are sensitive to or have ever had an allergic reaction to diphenhydramine hydrochloride or other antihistamines
h. Possible food and prescription drug Interaction. Benadryl may increase the effects of alcohol, and alcohol may increase the sedative effects of Benadryl. Do not drink alcohol while taking this medication. If Benadryl is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Benadryl with the following:
Antidepressant drugs known as MAO inhibitors, such as Parnate and Nardil
Sedative/hypnotics such as Halcion, Nembutal, and Seconal
Tranquilizers such as Xanax and Valium
a. The names given are the Generic name, you need to find the Brand name and the company that produces it.
Loradatine : Claritin, Schering-Plough
b. What is the mechanism of action.
Like other H1-blockers, loratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Claritin also has a weak affinity for acetylcholine and alpha-adrenergic receptors.
c. What is the use of the medication. The specific conditions that are treated with it.
Claritin is an antihistamine that relieves the sneezing, runny nose, stuffiness, itching, and tearing eyes caused by hay fever or other upper respiratory allergies. It also relieves the swollen, red, itchy patches of skin caused by …show more content…
hives. Claritin is also available as an over-the-counter product.
d. Side Effect of the prescription drug.
Common side effects include: dizzines drowsiness dry mouth
This medicine can cause excitement especially in children.
See a doctor immediately if you experience: fast or irregular heartbeat mental or mood changes tightness in the chest unusual tiredness or weakness.
e. Any important fact that calls your attention. If you have liver or kidney disease, your doctor should prescribe a lower starting dose of Claritin.
f. Dosage and how should it be taken.
10 mg tablets per day, to be administered orally
g. When should not be prescribed.
Do not take Claritin if you are sensitive to or have ever had an allergic reaction to it. Make sure your doctor is aware of any drug reactions that you have experienced.
h. Possible food and prescription drug Interaction. Although no harmful interactions with Claritin have been reported, there is a theoretical possibility of an interaction with the following drugs: Antibiotics such as erythromycin Cimetidine (Tagamet) Ketoconazole (Nizoral) Do NOT take this medicine with orange, apple or grapefruit juice. The levels of this medicine in your blood may be decreased by 70%.
Diphenydramine
a. The names given are the Generic name, you need to find the Brand name and the company that produces it. diphenydramine: Benadryl, Pfizer
b. What is the mechanism of action Blocks cellular histamine receptors; decreases vasodilation; decreases motion sickness. Reverses extrapyramidal reactions.
c. What is the use of the medication. The specific conditions that are treated with it. Benadryl is an antihistamine with drying and sedative effects. It relieves red, inflamed eyes caused by food allergies and the itching, swelling, and redness from hives and other rashes that are caused by mild allergic reactions. It also relieves the sneezing, coughing, runny or stuffy nose, and red, teary, itching eyes caused by seasonal allergies (hay fever) and the common cold. Benadryl is also used to treat allergic reactions to blood transfusions, to prevent and treat motion sickness, and, with other drugs, to treat anaphylactic shock (severe allergic reaction) and Parkinson's disease, a nerve disorder characterized by tremors, stooped posture, shuffling walk, muscle weakness, drooling, and emotional instability.
d. Side Effect of the prescription drug. • common side effects may include: Disturbed coordination, dizziness, excessive calm, increased chest congestion, sleepiness, stomach upset • Less common or rare side effects may include: Anaphylactic shock (extreme allergic reaction), anemia, blurred vision, chills, confusion, constipation, convulsions, diarrhea, difficulty sleeping, double vision, dry mouth, nose, throat, early menstruation, excessive perspiration, excitation, fast, fluttery heartbeat, fatigue, frequent or difficult urination, headache, hives, inability to urinate, increased sensitivity to light, irregular heartbeat, irritability, loss of appetite, low blood pressure, nausea, nervousness, rapid heartbeat, rash, restlessness, ringing in the ears, stuffy nose, tightness of chest and wheezing, tingling or pins and needles, tremor, unreal or exaggerated sense of well-being, vertigo, vomiting
e. Any important fact that calls your attention Antihistamines may produce excitability in children. In the elderly they may cause dizziness, excessive calm, or low blood pressure.
f. Dosage and how should it be taken. Benadryl reaches its peak effect in 1 hour, and 1 dose will continue to work for 4 to 6 hours.
ADULTS
The usual recommended dose is 25 to 50 milligrams 3 or 4 times daily. The sleep-aid dosage is 50 milligrams at bedtime.
Motion Sickness
For prevention of motion sickness, take the first dose 30 minutes before exposure to motion; take the other doses before meals and at bedtime for as long as the motion continues.
CHILDREN (OVER 20 POUNDS)
The usual dose is 12.5 to 25 milligrams, 3 to 4 times daily. A child should not take more than 300 milligrams a day.
This medication should not be used as a sleep aid for children under age 12.
Your physician will determine the best use of the drug in response to its effects on the child.
g. When should not be prescribed. Benadryl should not be used in newborn or premature infants, or if you are breastfeeding your infant. Do not take this medication if you are sensitive to or have ever had an allergic reaction to diphenhydramine hydrochloride or other antihistamines
h. Possible food and prescription drug Interaction. Benadryl may increase the effects of alcohol, and alcohol may increase the sedative effects of Benadryl. Do not drink alcohol while taking this medication. If Benadryl is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Benadryl with the following:
Antidepressant drugs known as MAO inhibitors, such as Parnate and Nardil
Sedative/hypnotics such as Halcion, Nembutal, and Seconal
Tranquilizers such as Xanax and Valium