Lorenzo Oil

1. What was Augusto Odone’s plumbing example used to explain? How do analogies often help us understand a scientific problem? It was used to explain how saturated fats were not getting trough Lorenzo’s system because it was clogged up. Analogies help you understand problems by giving you a related example that most people understand. 2. How did diet affect this disease’s progression? And what was “Lorenzo’s oil”? Why was it special? Diet helped and harmed Lorenzo. Lorenzo’s oil is a 4:1 mixture of glyceryl trierucate and glyceryl trioleate (the triglyceride forms of erucic acid and oleic acid), prepared from rapeseed oil and olive oil. It is used in the investigational treatment of asymptomatic patients with adrenoleukodystrophy (ALD). 3. How did Augusto use modeling (paper clips) to solve a scientific problem? Can you think of another “great discoveries” that employed models? A paper clip represented the two carbon unit and he added paper clips until he produced chains of 24 or 26 carbons. The discovery of DNA employed the use of a ball and stick model of the double helix. 4. Why did they encounter resistance from the medical community and from the support organization? What did you learn from observing this behavior? They encountered resistance because the people of the medical community and the support organization because they didn’t think that they really could have came up with a cure or way to control it. After observing this behavior I see that you can’t really doubt people’s thoughts or there beliefs be because in the long run they might be right. 5. We can learn anything we want to. Most of use will and should regard ourselves as “lifelong learners”. How did Augusto and Michaela demonstrate this? They demonstrated by learning everyday about the disease and doing research. Everyone is a life long learner because you learn something new every day and new technology comes out every day. 6. As you reflect on this movie, hoe did the