Mary Collins
Johnson
Anatomy Physiology
Period 1
1 December, 2014 Lou Gehrig’s Disease
Amyotrophic Lateral Sclerosis (ALS) Of all diseases, one of the strongest and well known as Lou Gehrig’s Disease
.
Lou
Gehrig’s Disease
, also commonly known as ALS
(
which stands for Amyotrophic lateral sclerosis )
, is a neurodegenerative, meaning degrading of neurons in the brain, disease affecting the brain cells and spinal cord
. It kills both upper and lower neurons in the motor cortex of the brain, the brainstem, and spinal cord
. It is rapidly progressively, and invariably fatal to those who have it
.
The first recorded notes of ALS date back to 1874
,
and was discovered by JeanMarie
Charcot, who was a noted neurologist
. Many know ALS as Lou Gehrig’s disease
,
named after the baseball player whose career came to an end through ALS
.
After this, ALS became well known. Collins 1
There is no cure for ALS, although in 1995 the first drug treatment was approved for
ALS symptoms. It is called Riluzole
.
It’s believed to help decrease damage to the motor neurons. This is because it decreases the rate of glutamate
.
Glutamate is an amino acid that transmits messages to molecules, and those with ALS have higher levels of glutamate than average . There are some side effects of the medication including dizziness and reduced leukocytes in the blood
.
There are other drugs that can be given over the counter to help reduce any pains or fatigue, which can aid those with progressing ALS, Many who suffer from ALS have also been known to suffer from depression, so many take antidepressants as well
.
ALS symptoms are very subtle, and tend to be overlooked by most
.
Recorded symptom of ALS include shakiness, twitching, cramping, or stiffness of muscles
. Slurring of speech and difficulty chewing or swallowing have also been recorded to be symptoms of ALS
.
A