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MZ Twins: A Genetic Case Study

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MZ Twins: A Genetic Case Study
The cause of phenotypic discordance in MZ twins has traditionally been attributed to postnatal environmental factors unique to the individual siblings of the pair (Poulsen, 2007). Genetic differences between MZ twins are more readily found and expressed through DNA methylation rather than point mutations and chromosomal abnormalities. In the case for women, epigenetic variations can be explained by X-chromosomal inactivation. Differences in DNA methylation and histone acetylation explain that young MZ twins are near identical, whereas elderly MZ twins express variations on several tissues by epigenetic markings. It can be concluded that elderly twins obtain a greater variability through age in comparison to younger MZ twins. MZ twins who are

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