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MENDELIAN GENETICSDEXTER GICARO BALBOAUNORCoverage of this
MENDELIAN GENETICS
DEXTER GICARO BALBOA
UNO-R

Coverage of this Lecture
• Mendelian Genetics
• Extension of Mendel’s Laws
• Problem Sets

Mendelian Genetics

•

Also known as
Transmission Genetics

•

Explores how the genetic material is inherited from generation to generation Mendelian Genetics
 The first significant insights into the mechanisms involved in inheritance occurred in 1866 with the works of Gregor Johann
Mendel
 His publication lay the foundation for the formal discipline of genetics

 Father of Modern Genetics

Mendelian Genetics
• Mendel has been credited with discovering the first two laws of inheritance:
 Law of Segregation: o unit factors for the same character segregate independently from one another during the formation of gametes o During meiosis, homologous chromosomes pairs segregate/ separate from each other independently of one another toward the opposite poles of the cell to form progeny cells of different chromosome combinations

Mendelian Genetics
• Mendel has been credited with discovering the first two laws of inheritance:
 Law of Independent Assortment: o “the behavior of each pair of differing traits in a hybrid association is independent of all other differences in the two parental strand” o During the course of segregation of alleles different genes assort/ combine indefinitely and independently with other alleles of other genes o Exception “Linked Genes”

Reviews on Mendel’s Paper: Mendel is not a Mendelian

 About speciation and hybridization
 He tried to find a generally applicable law governing the formation and development of hybrids
 Mendel never mentioned the now-famous 9:3:3:1 ratio in his paper
 Do not announced any major discoveries or laws
 Do not introduce the concept of equivalence
 Do not study the inheritance of characters

 Mendel’s work went unnoticed until 1900s, but in the ensuing years the concept of the gene as a distinct hereditary unit was established  The ways in which genes, as members
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