Is complements nerve conduction studies and serves a critical role in the evaluation of both muscle and nerve diseases. Recording the electrical activity of the muscle cell membrane with a needle electrode inserted in the muscle, the motor unit potential (MUP) can be recorded. Electromyography is performed using an instrument called electromyograph, to produce a record called electromyogram.
This represents the summated electrical activity of action potentials of all of the muscle fibers making up that motor unit.
Motor unit is the smallest functional unit of the skeletal muscle which can be voluntarily activated and consistent of an anterior horn cell, its axon and all the muscle fiber it innervates (8).
Electromyographic …show more content…
4-Complex repetitive discharge.
5-Fasciculation potential.
6-Myokymic potential.
7-Neuromyotonic potential.
C- Muscle potentials evoked by isolated discharges of motor neurons are recorded with mild voluntary contraction of the muscle motor units potentials (MUP). D- The change in electrical potential is associated as the level of muscle contraction gradually increased and eventually reaches a maximum (recruitment and interference pattern)(44).
1.4.4.2 Pioneered corneal confocal microscopy (CCM) a rapid and noninvasive ophthalmic technique. The technique has been shown to be reproducible and highly sensitive and specific in the diagnosis of early nerve damage, even in patients without symptoms or signs and in those without neurophysiologic abnormalities (49) ( figure 11). 1.4.4.3 Testing sudomotor function, or the function of sweat glands one of the diagnostic tool for early detection of DPN in diabetic patients . Sweat glands are innervated by small unmyelinated cholinergic sympathetic fibers that could be affected early in the course of diabetes mellitus (38)(50).
1.4.4.4 Skin biopsy can give a dependable quantification of somatic and autonomic small nerve fibers using both bright field immunohistochemistry and indirect immunofluorescence