Neuron Impulse

t is important to mention the Neuron as carrier impulses from the CNS to the periphery, the peripheral nerves in turn have the funsion to carry messages from one part of the organism to another, so we can understand the action of these drugs.
They act in the prevention, generation and propagation of the nervous impulse. Acting on the blocking of the depolarization initiation, allowing Na + to enter the nerve cell from rest to the trigger threshold (- 50a - 60 mV) would consequently impede the initiation and propagation of the impulse. Therefore, in the maintenance of equilibrium, Repolarization arises by actively transferring ions from Na + outwards and K into the cell by the Sodium-Potassium pump, requiring energy. The propagation of the Nervous impulse initiated the impulse by a stimuluscircula along the axon and it does it in a single sense although it does not propagate of equal way in the different amielinicos nerves and myelinic nerves this last one favors the transit of the impulse in a saltatory way by the Nodules that it presents.
The mode and site of action of these drugs are performed and interfere (altering the resting state of the nerve membrane,
The nerve, chemical, mechanical or temperature stimulus produces a pulse that travels through the nerve fiber to spread steadily, regardless if the initial stimulus persists or Varies, this is only possible because the impulse travels through the energy released into the nerve fiber itself. (1)
Mechanisms for local anesthetics to be accurate in their use.
1) Structure of Peripheral Nerves.
2) Physiology of Peripheral Nerves.
3) Electrophysiology of Nerve Conduction.
4) Electrochemistry of the conduction Nervous (Exitacion of the Membrane).
5) Propagation of the Nervous Impluso.
6) Mode and Site of Action of Local Anesthetics.
The action of these drugs is to prevent the generation and propagation of the nerve