Ambar Alvarez
California State University – San Marcos
NURS 312 Pharmacology and Pathophysiology
Alham Abuatiq. PhD. MSN.RN
July 30, 2017
Case Study# 2
1. Heart failure (HF) is a syndrome that involves dysfunction of the cardiac muscle, it occurs with “any of disorders that damage or overwork the heart muscle” (Karch, 2017 p.751). Some of the disorders that may lead to HF are: coronary artery disease, cardiomyopathy, hypertension, and valvular heart disease (Karch, 2017). What ends up happening as a result of these disorders, is that the heart muscle cannot effectively pump blood throughout the vascular system (Karch, 2017). In left-sided heart failure, the “blood backs up into the lungs which leads to pulmonary vessel congestion and fluid leakage into the alveoli and lung tissue” (Karch, 2017 p.752). In right-sided failure, the blood backs up in the venous system, which may lead to liver congestion and edema of the legs and feet (Karch, 2017). …show more content…
Digoxin “increases intracellular calcium and allows more calcium to enter myocardial cells during depolarization” (Karch, 2017 p.756). The increase in calcium leads to: increased force of contractions, increased cardiac output and renal perfusion, slower heart rate, and decreased conduction velocity through the AV node (Karch, 2017). This medication is indicated for HF, a-flutter, a-fib, and paryoxysmal atrial tachycardia (Karch,