Organism Project
Family | Campylobacteraceae | Genera | Helicobacter | Genus/Species | Helicobacter pylori | Description |
Helicobacter pylori is a motile, curved, spiral, or straight, slightly plump, gram-negative rod. It is believed to be a major cause of gastritis and peptic ulcers although it resides solely on the gastric mucosa and does not enter cells.
Microscopic description for the family Campylocbacteraceae | Shape: Spiral ShapedStaining Reaction (Gram): NegativeUnique Characteristic: Spiral Shaped with Flagellum Single/Clusters: ClusterSpore Formation: NoDimension: 2-4 um x 0.5-1.0 um | | |
Macroscopic appearance on growth media | Whole colony appearance: CircularMargin (Edge): EntireElevation: Flat and raisedGrowth in liquid medium:Pattern of growth on media: BeadedSize: SmallTexture: RoughAppearance on routine isolation media: DullAppearance on special media: DullOptical Property: Opaque | |
Defining Characteristics for the family | Non-Enteric gram negative rod Many | | | | | | Growth Conditions Most grow well at 42Degrees Celsius |
Defining characteristics for the genus/species Helicobacter pylori | Natural Habitat, Geographic distribution Worldwide | Mode of human infection a) Unknown , but thought to be fecal-oral or oral-oral | Media for optimal growth in laboratory cultures 1. Urease Test 2. Selective agar media | Key Biochemical reactions 1. All H. pylori isolates were Gram-negative spiral to coccobacilli and shared the characteristic catalase, urease, and oxidase production. 2. Urea agar- correlated with the change in the color of the slant MCUA tube from orange to pink that occurred at the same time thus giving an additional evidence for the presence of H. pylori |
Clinical syndromes for the species Helicobacter pylori | Gastritis H. pylori works by attacking the mucous shield that coats the stomach and duodenum. When the bacterium creates a wound in the
Helicobacter pylori is a motile, curved, spiral, or straight, slightly plump, gram-negative rod. It is believed to be a major cause of gastritis and peptic ulcers although it resides solely on the gastric mucosa and does not enter cells.
Microscopic description for the family Campylocbacteraceae | Shape: Spiral ShapedStaining Reaction (Gram): NegativeUnique Characteristic: Spiral Shaped with Flagellum Single/Clusters: ClusterSpore Formation: NoDimension: 2-4 um x 0.5-1.0 um | | |
Macroscopic appearance on growth media | Whole colony appearance: CircularMargin (Edge): EntireElevation: Flat and raisedGrowth in liquid medium:Pattern of growth on media: BeadedSize: SmallTexture: RoughAppearance on routine isolation media: DullAppearance on special media: DullOptical Property: Opaque | |
Defining Characteristics for the family | Non-Enteric gram negative rod Many | | | | | | Growth Conditions Most grow well at 42Degrees Celsius |
Defining characteristics for the genus/species Helicobacter pylori | Natural Habitat, Geographic distribution Worldwide | Mode of human infection a) Unknown , but thought to be fecal-oral or oral-oral | Media for optimal growth in laboratory cultures 1. Urease Test 2. Selective agar media | Key Biochemical reactions 1. All H. pylori isolates were Gram-negative spiral to coccobacilli and shared the characteristic catalase, urease, and oxidase production. 2. Urea agar- correlated with the change in the color of the slant MCUA tube from orange to pink that occurred at the same time thus giving an additional evidence for the presence of H. pylori |
Clinical syndromes for the species Helicobacter pylori | Gastritis H. pylori works by attacking the mucous shield that coats the stomach and duodenum. When the bacterium creates a wound in the
References: | http://www.cdc.gov/ulcer/keytocure.htm | Scott M Kulich MD, PhD and Sydney Finkelstein, MD (1999). Case 196 Irritable Bowel Syndrome .http://path.upmc.edu/cases/case196.html |