Oxidative Stress Research Paper
The Danger of Oxidative Stress
A look into the mechanism and effects of Oxidative Stress
Annisa Rumahorbo
3/17/2017
Abstract
The author's purpose of this paper was to determine if oxidative stress could be related to major diseases. The author read and analyzed several articles regarding free radicals and oxidative stress and also a number of field reports of experiments that related to oxidative stress and other diseases. Most of the data the author uses were found from the online database. The author first covers what free radicals are and how they operate. After that, the author presents how the free radicals are the major factor of oxidative stress that leads to the discussion the damage caused by oxidative stress. The author …show more content…
We never think much about what is happening within our body systems when we do this activity and how it could produce something dangerous without us realizing it. When we breathe, we inhale oxygen, like any other aerobic organism on the planet, and this oxygen is used as an electron receiver for our cellular respiration mechanism. The process of cell respiration in cells that use oxygen as the last electron receiver and enzymes, produces oxygen free radicals as side products. To prevent the hazardous effects of oxygen free radicals, the human body produces antioxidants, which are molecules that donate electron to free radical molecules and stabilize them before any harm is being done to the body (Keaney, 59). There should be a balance between the amount of oxygen free radicals and antioxidants, and any disproportionate amount of each in respect to the other would lead to the oxidative stress which is the focus of this paper.
The majority of scientific researches related to the Oxidative Stress began about 60 years ago, when Rebeca Gerschman published an article about oxygen poisoning and X-irradiation. This article focuses mainly on the indirect effect of OH and H radicals in ionizing radiation that eventually causes the production of H2O2 and also hypothesizes that the inactivation of SH (thiol) group is one of the main causes of this toxic effect (Gerschman et al., 624). As the time passed by, many other researchers through their experiments found
A look into the mechanism and effects of Oxidative Stress
Annisa Rumahorbo
3/17/2017
Abstract
The author's purpose of this paper was to determine if oxidative stress could be related to major diseases. The author read and analyzed several articles regarding free radicals and oxidative stress and also a number of field reports of experiments that related to oxidative stress and other diseases. Most of the data the author uses were found from the online database. The author first covers what free radicals are and how they operate. After that, the author presents how the free radicals are the major factor of oxidative stress that leads to the discussion the damage caused by oxidative stress. The author …show more content…
We never think much about what is happening within our body systems when we do this activity and how it could produce something dangerous without us realizing it. When we breathe, we inhale oxygen, like any other aerobic organism on the planet, and this oxygen is used as an electron receiver for our cellular respiration mechanism. The process of cell respiration in cells that use oxygen as the last electron receiver and enzymes, produces oxygen free radicals as side products. To prevent the hazardous effects of oxygen free radicals, the human body produces antioxidants, which are molecules that donate electron to free radical molecules and stabilize them before any harm is being done to the body (Keaney, 59). There should be a balance between the amount of oxygen free radicals and antioxidants, and any disproportionate amount of each in respect to the other would lead to the oxidative stress which is the focus of this paper.
The majority of scientific researches related to the Oxidative Stress began about 60 years ago, when Rebeca Gerschman published an article about oxygen poisoning and X-irradiation. This article focuses mainly on the indirect effect of OH and H radicals in ionizing radiation that eventually causes the production of H2O2 and also hypothesizes that the inactivation of SH (thiol) group is one of the main causes of this toxic effect (Gerschman et al., 624). As the time passed by, many other researchers through their experiments found