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Pathophysiology Of Obese

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Pathophysiology Of Obese
When a person eats a lot and very quickly, the gastric contents in the stomach increases causing an elevation in intragastric pressure and resulting in increased pressure on the lower esophageal sphincter. LES will not be able to overcome this pressure and causes reflux.

Studies have shown that GERD is highly dominant in obese patients and one of the factor for this condition is a high body mass index (BMI).(10) The pathophysiology of GERD in non-obese patients might differ from obese patients. Thus, obesity should be controlled first before reflux correction. The mechanism by which a high BMI rises esophageal acid exposure is not understood completely. Increased intragastric pressure and gastroesophageal pressure gradient, incompetence of
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