Pharma
Class of antibiotic w/c GABHS is very sensitive to: Penicillin - no reported resistance despite decades of use
Single dose of IM Pencillin is effective
Formulation for children because of less pain: combination of Penicillin G Benzathine and Penicillin G Procaine
Oral penicillin is a good alternative - Penicillin V
4 Alternatives to Penicillin, if they have allergy:
Erythromycin
Cephalosporins
Clindamycin
Azithromycin
What is the advantage of using penicillin as much as possible? Penicillin has been the only one that has been demonstrated conclusive job in preventing rheumatic fever.
MRSA - Methicillin Resistant Staphylococcus aureus
DOC: Vancomycin IV - a glycopeptide
Active against: All gram +
Preferred 2nd DOC: Trimethophrim Sulfa IV
Normal site of carriage in 20% of adults of S. aureus including MRSA: anterior nares
Class of antibiotic of methicilllin - PRSP (Penicillinase Resistant Synthetic Penicillin)
Penicillinase - an enzyme that attacks Penicillin, a.k.a. beta-lactamase
MRSA - resistant to penicillinase (beta-lactamase) and methicillin (PRSP)
What non-drug strategy may be effective w/ early mastitis in the post-partum breast? Increase Breastfeeding!
Likely organism w/ mastitis, esp. severe? S. aureus
DOC for severe mastitis: Dicloxocillin, a PRSP
DOC if allergic to dicloxocillin: Cefazoline IV, a 1st gen cephalosporin (best for gram + including S. aureus, except MRSA)
If the patient has breast abscess instead of mastitis, what two non-drug strategies should be employed first?
Discontinue nursing
Incise and drain the abscess
Likely organism in a breast abscess? S. aureus
Alternatives DOC: Nafcillin or Oxacillin IV, which are PRSP
Allergy to both, alternative is Cefazolin IV
Vitamin for pregnant, or those who wish to become pregnant: Folic Acid
Most common organism in osteomyelitis in any age group except in puncture wounds and diabetes: S. aureus
2 DOC of osteomyelitis for children:
Single dose of IM Pencillin is effective
Formulation for children because of less pain: combination of Penicillin G Benzathine and Penicillin G Procaine
Oral penicillin is a good alternative - Penicillin V
4 Alternatives to Penicillin, if they have allergy:
Erythromycin
Cephalosporins
Clindamycin
Azithromycin
What is the advantage of using penicillin as much as possible? Penicillin has been the only one that has been demonstrated conclusive job in preventing rheumatic fever.
MRSA - Methicillin Resistant Staphylococcus aureus
DOC: Vancomycin IV - a glycopeptide
Active against: All gram +
Preferred 2nd DOC: Trimethophrim Sulfa IV
Normal site of carriage in 20% of adults of S. aureus including MRSA: anterior nares
Class of antibiotic of methicilllin - PRSP (Penicillinase Resistant Synthetic Penicillin)
Penicillinase - an enzyme that attacks Penicillin, a.k.a. beta-lactamase
MRSA - resistant to penicillinase (beta-lactamase) and methicillin (PRSP)
What non-drug strategy may be effective w/ early mastitis in the post-partum breast? Increase Breastfeeding!
Likely organism w/ mastitis, esp. severe? S. aureus
DOC for severe mastitis: Dicloxocillin, a PRSP
DOC if allergic to dicloxocillin: Cefazoline IV, a 1st gen cephalosporin (best for gram + including S. aureus, except MRSA)
If the patient has breast abscess instead of mastitis, what two non-drug strategies should be employed first?
Discontinue nursing
Incise and drain the abscess
Likely organism in a breast abscess? S. aureus
Alternatives DOC: Nafcillin or Oxacillin IV, which are PRSP
Allergy to both, alternative is Cefazolin IV
Vitamin for pregnant, or those who wish to become pregnant: Folic Acid
Most common organism in osteomyelitis in any age group except in puncture wounds and diabetes: S. aureus
2 DOC of osteomyelitis for children: