In 1593, Spanish authorities in Manila authorized the dispatch of Franciscan missionaries to Japan. The Franciscan friar Luis Sotelo was involved in the support of the Dilao enclave between 1600 and 1608.
In the first half of the 17th century, intense official trade took place between the two countries, through the Red seal ships system. Thirty officials "Red seal ship" passports were issued between Japan and the Philippines between 1604 and 1616.
The Japanese led an abortive rebellion in Dilao against the Spanish in 1606-1607, but their numbers rose again until the interdiction of Christianity by Tokugawa Ieyasu in 1614, when 300 Japanese Christian refugees under Takayama Ukon settled in the Philippines. On November 8, 1614, together with 300 Japanese Christians Takayama Ukon left his home country from Nagasaki. He arrived at Manila on December 21 and was greeted warmly by the Spanish Jesuits and the local Filipinos there. The Spanish Philippines offered its assistance in overthrowing the Japanese government by invasion to protect Japanese Catholics. Justo declined to participate, and died of illness just 40 days afterwards. These 17th century immigrants are at the origin of some of today's 200,000-strong Japanese population in the Philippines.
More rebellions such as one known