UC-38 Dr. Alma Nacua
Autoimmune
Disease
Causes
Effects
Ankylosing spondylitis
Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called HLA-B27 are at significantly increased risk of developing ankylosing spondylitis.
Although other joints can be involved, ankylosing spondylitis (AS) primarily affects the spine. In this particular type of arthritis, the joints and ligaments of the spine become inflamed.
Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS)
Antiphospholipid syndrome can cause arterial or venous blood clots, in any organ system, or pregnancy-related complications.
Thrombocytopenia
Recurrent fetal loss
Blood clotting
Venous thrombosis
Arterial occlusions
Leg ulcers
Hemolytic anemia
Premature birth
Deep vein thrombosis
Stroke
Pulmonary embolism
Heart attack
Autoimmune Hemolytic Anemia (AIHA)
The causes of AIHA are poorly understood. The disease may be primary, or secondary to another underlying illness. The most common causes of secondary warm-type AIHA include lymphoproliferative disorders (e.g.,chronic lymphocytic leukemia, lymphoma) and other autoimmune disorders (e.g., systemic lupus erythematosus, rheumatoid arthritis, scleroderma, ulcerative colitis)
The effects are usually related to the lack of oxygen and manifest themselves in the form of weakness, lethargy, and an increase in the heart and respiration rate. Vomiting or abdominal pain may be present.
Gelacio, Seigfred Paul V. 14-UC-1882
UC-38