Respiratory Acidosis and Alkalosis
Activity 1: Normal Breathing
1. At 20 seconds, pH = 7.38 2. At 40 seconds, pH = 7.38 3. At 60 seconds, pH = 7.38 4. Did the pH level of the blood change at all during normal breathing? If so, how? No. 5. Was the pH level always within the “normal” range for the human body? Yes. 6. Did the PCO2 level change during the course of normal breathing? If so, how? No.
Activity 2a: Hyperventilation – Run 1
1. At 20 seconds, pH = 7.45 2. At 40 seconds, pH = 7.5 3. At 60 seconds, pH = 7.66 4. Maximum pH = 5. Did the pH level of the blood change at all during this run? If so, how? Yes. pH increased and decreased significantly. 6. Was the pH level always within the “normal” range for the human body? If not, when was the pH value outside of the normal range, and what acid/base imbalance did this pH value indicate? No. pH was outside the normal range at around 5 seconds after hyperventilation started. The acid/base imbalance indicated by the pH value was respitory alkalosis 7. Did the PCO2 level change during the curse of this run? If so, how? Yes. Progressively dropped. 8. If you observed an acid/base imbalance during this run, how would you expect to renal system to compensate for this condition? Hypoventilation causes an increase in Pco2, generation of H+ causes a decrease in plasma pH, secretion of HCO3- into urine causes a decrease in plasma pH. 9. How did the hyperventilation trace differ from the trace for the normal breathing? Did the tidal volumes change? The hyperventilation trace went to higher and lower extremes than the trace for normal breathing. Yes 10. What might cause a person to hyperventilate? Traveling to a higher altitude, fever, and anxiety.
Activity 2b: Hyperventilation – Run 2
1. What happened to the trace after the 20-second mark when you stopped the hyperventilation? Did the breathing