Physiology Notes
Self-renewal and differentiation are fundamental stem cell fate decisions, which are essential for normal tissue development, homeostasis, and repair actin cytoskeleton and
Rho-GTPases, mediate downstream signal transduction
Serum response factor
(SRF) and yes-associated protein (YAP) are two examples of mechano-sensitive transcription factors, which have recently been implicated in epidermal and mesenchymal stem cell differentiation
Lab notes:
Passive processes: transport driven by concentration , or pressure
Active process: cell provides ATP to power transport
Diffusion: 1: simple; no membrane proteins , 2 : facilitated(passive): requires membrane bound carrier protein that assits transport …….. both deal with gradients, kinectic energy and equilibrium * Higher to lower concentraion
Osmosis; water moves form higher to lower concentration
Filtration: occurs only across capillary walls
Vesicular transport(active process); phagocytosis, endocytosis, pinocytosis, and excocytosis
KE= ½ mv^2
Driving force of diffusion is…. Kinetic energy
Molecules need a carrier protein to move across membrane b/c…. the are lipid insoluable, or are too large
Does not affect facilitated diffusion; amount of ATP
Simple diffusion occurs without membrane proteins and facilitated require a carrier protein to assist in transport. They are similar because they both move along the concentration grad ent (from high to love),
The greater the concentration difference between one side of the membrane and the other, the greater the rate of facilitated diffusion
Fully permeable(permeable to solutes and water)
Water moves down the concentration gradient, or towar the solution with the highest concentration solutes….resulting in a volume increase
Osmotic pressure(closed system)(mmHG), the more impermeable the higher the osmotic pressure
Tonicity(shrink or swell); how a solution affects the volume of a cell
Isotonic: same inside and outside
Hypertonic: higer
Rho-GTPases, mediate downstream signal transduction
Serum response factor
(SRF) and yes-associated protein (YAP) are two examples of mechano-sensitive transcription factors, which have recently been implicated in epidermal and mesenchymal stem cell differentiation
Lab notes:
Passive processes: transport driven by concentration , or pressure
Active process: cell provides ATP to power transport
Diffusion: 1: simple; no membrane proteins , 2 : facilitated(passive): requires membrane bound carrier protein that assits transport …….. both deal with gradients, kinectic energy and equilibrium * Higher to lower concentraion
Osmosis; water moves form higher to lower concentration
Filtration: occurs only across capillary walls
Vesicular transport(active process); phagocytosis, endocytosis, pinocytosis, and excocytosis
KE= ½ mv^2
Driving force of diffusion is…. Kinetic energy
Molecules need a carrier protein to move across membrane b/c…. the are lipid insoluable, or are too large
Does not affect facilitated diffusion; amount of ATP
Simple diffusion occurs without membrane proteins and facilitated require a carrier protein to assist in transport. They are similar because they both move along the concentration grad ent (from high to love),
The greater the concentration difference between one side of the membrane and the other, the greater the rate of facilitated diffusion
Fully permeable(permeable to solutes and water)
Water moves down the concentration gradient, or towar the solution with the highest concentration solutes….resulting in a volume increase
Osmotic pressure(closed system)(mmHG), the more impermeable the higher the osmotic pressure
Tonicity(shrink or swell); how a solution affects the volume of a cell
Isotonic: same inside and outside
Hypertonic: higer