Puurines Breakdown Lab Report
1.1: Thesis outline
Purines breakdown by the body will form a chemical called uric acid. Uric acid mostly can be found in foods and drinks like dried been and pears. Normally, most of the uric acid dissolves in blood and move from blood to the kidneys. High level uric acid kidney or blood caused some bad effect such as leukemia, hyperuricemic and lymphoma. Therefore, the electrochemical method (graphene oxide modified glassy carbon electrode method) are introduced to detect the uric acid in human urine sample. Previously, the electrode is modified with noble metal nanoparticles such as Pd, Pt and Au. Among the Pd, Au and Pt, Au has good prospect and choose to determine uric acid due to unique structure and excellent conductivity. Furthermore, the method such as capillary electrophoresis and high performance liquid chromatography (HPLC) are used by the previous researcher are quite time consuming and not environmental friendly and therefore, …show more content…
The test for uric acid urine is for measure the quantity of uric acid in a sample of urine collected over 24 hours. Uric acid is formed from the natural breakdown of your body's cells and produce from the foods that we ate. Our kidneys take uric acid leave from your blood and put it into urine so that it can excrete your body. However if there are many uric acid in our body, the level in the urine can become too high and if our kidneys aren't function the way well, the level of uric acid in the urine can become too high. High levels of uric acid can let the crystals to build in joints and causes a painful problem called gout. If gout do not treat well, the crystals can accumulate and form the hard lumpy deposits called tophi. Furthermore, high uric acid levels will also cause kidney stones and therefore that is crucial to develop a sensitive method for their
Purines breakdown by the body will form a chemical called uric acid. Uric acid mostly can be found in foods and drinks like dried been and pears. Normally, most of the uric acid dissolves in blood and move from blood to the kidneys. High level uric acid kidney or blood caused some bad effect such as leukemia, hyperuricemic and lymphoma. Therefore, the electrochemical method (graphene oxide modified glassy carbon electrode method) are introduced to detect the uric acid in human urine sample. Previously, the electrode is modified with noble metal nanoparticles such as Pd, Pt and Au. Among the Pd, Au and Pt, Au has good prospect and choose to determine uric acid due to unique structure and excellent conductivity. Furthermore, the method such as capillary electrophoresis and high performance liquid chromatography (HPLC) are used by the previous researcher are quite time consuming and not environmental friendly and therefore, …show more content…
The test for uric acid urine is for measure the quantity of uric acid in a sample of urine collected over 24 hours. Uric acid is formed from the natural breakdown of your body's cells and produce from the foods that we ate. Our kidneys take uric acid leave from your blood and put it into urine so that it can excrete your body. However if there are many uric acid in our body, the level in the urine can become too high and if our kidneys aren't function the way well, the level of uric acid in the urine can become too high. High levels of uric acid can let the crystals to build in joints and causes a painful problem called gout. If gout do not treat well, the crystals can accumulate and form the hard lumpy deposits called tophi. Furthermore, high uric acid levels will also cause kidney stones and therefore that is crucial to develop a sensitive method for their